Scientific Director I, Translational Precision Medicine, Neuroscience

About the role

Discover neurobiological mechanisms of disease that elucidate patient subtypes; mechanisms of action, response, or resistance, and advance the development of novel interventions.

Develop testable hypotheses related to neurobiological pathways, neuronal circuitry, cognitive or behavioral domains, or functional markers of disease or patient subtypes that will advance pipeline and disease area goals.

Collaborate with PMed DAS leads and other functional leads, develop and execute / drive execution of operationally-sound approach and generate actionable outcomes.

Shape and enhance efforts in human neuroscience, including promoting research synergies with other areas of R&D, aligned to disease area strategic goals.

Drive scientific strategy for translational biomarker development and discovery target validation / MOA projects.

Lead the design of clinically translational experiments in collaboration with PMED, clinical leads, or discovery research translational teams that achieve disease area strategic goals.

Establish external collaborations to augment internal translational efforts and expand experimental design options.

Achieve quality and effectiveness of major project plans within precision medicine through sound design and early risk assessment.

Advance clinical translational efforts through alignment with relevant stakeholders and leadership, and navigation of current and emerging business challenges to goal achievement.

Communicate scientific expertise and learnings by proactively advising and knowledge-sharing with subordinates, peers, and senior management.

Qualifications

• Bachelor’s Degree in Science related field with 20 years of related work; Master’s Degree Science with 14 years of related work; PhD or equivalent professional terminal degrees (or PharmD/MD) in Science or related field with 10 years of related work experience.
• Relevant biology, target validation, and biomarker research experience in the areas of neural circuits, functional domains in clinical sciences using clinical science approaches (e.g., cognitive, emotional, behavioral), liquid-based methods, or structural and functional imaging.
• Expert in one/at least one.
• Knowledge of the drug development process and how clinical translation fits within this.
• Proven track record of integration in the drug development process having advanced one or more assets beyond.
• Proven leadership ability to direct, lead, and learn from cross-functional teams.
• Strong presentation skills required, with the ability to present data successfully to scientists and nonscientists.
• Tests new innovations and manages to reality.