Research Technician II- Diamond Lab

About the Role

This entry-level research technical role participates in planned research projects by performing research protocols, experimental procedures, and other laboratory tasks under direct supervision. The position may occasionally exercise minimal discretion and judgment in the execution and interpretation of experiments and derived data.

We are a hepatology lab in the Abramson Building at CHOP focused on dysregulated immune responses that result in liver failure in children. As part of understanding these diseases in the liver, we collect patient samples during procedures and work with mouse models to find treatments for these disorders. The lab works closely with a larger group at CHOP focused on immune dysregulation disorders across various disciplines, including neonatology, rheumatology, and gastroenterology.

Techniques We Use

• Flow cytometry
• Cell sorting
• qPCR
• Microscopy
• Single-cell next-generation sequencing
• Spatial transcriptomics
• ELISA assays
• Mouse models of human diseases (e.g., Hemophagocytic Lymphohistiocytosis, Macrophage Activation Syndrome, acute immune-mediated hepatitis)

This position will receive extensive training in these techniques during your time in the lab.

Team Overview

You will play an important role in the lab’s mission to further the understanding of the interaction between the immune system and liver function. The lab is collaborative, with a focus on scientific discovery and teamwork. Current team members include two lab technicians, a bioinformatics specialist, and multiple members at various levels of scientific training. We aspire to be a lab full of kind, collaborative, and motivated individuals with diverse backgrounds and experiences.

Responsibilities

• Performs routine tests and experiments under the direction of the principal investigator, supervisor, or other designee.
• Performs research procedures on experimental samples as directed.
• Records and checks experiments and results for completeness and accuracy.
• Performs calculations and maintains appropriate logs and lab notebooks.
• Performs tasks that require familiarity with fundamental techniques and lab equipment.
• May assist with planning specific research protocols and procedures.
• Maintains office, lab area, solutions, reagents, supplies, and equipment; disposes of specimens, media, and other materials using appropriate procedures.
• Assists in the care and maintenance of lab equipment.
• May coordinate schedules of tests and procedures.
• Attends courses, seminars, and lab meetings to expand knowledge of research and laboratory techniques.
• Records results, organizes data, and maintains lab notebooks in an organized manner.
• Compiles and helps analyze data; prepares charts, graphs, and results of studies as directed.
• Conducts literature searches as directed.

Requirements

• High School Diploma or GED (Required).
• Associate's or Bachelor's Degree (Preferred).
• At least one (1) year of related classroom experience or successful completion of a technical training program (e.g., Wistar, WPSI) and research laboratory experience (Required).
• At least two (2) years of related classroom experience or successful completion of a technical training program (e.g., Wistar, WPSI) and research laboratory experience (Preferred).

Skills and Abilities

• Intermediate understanding of lab procedures, protocols, and equipment.
• Basic exposure to lab-specific experiments, techniques, and scientific analysis.
• Excellent verbal and written communication skills.
• Excellent organizational skills.
• Solid critical thinking and problem-solving skills.
• Solid analytical skills.

Pay

Salary range: $43,900.00 - $54,800.00 annually. Salary ranges are shown for full-time jobs; part-time pay will be adjusted accordingly. Factors such as skills and experience may result in an offer above the noted range.

Schedule

Day shift (United States of America).