Research Specialist / Scientist, Assay Development
Altos Labs · San Francisco, CA · 1 mo ago
Analyst$130k–$166k/yrFull-time
Responsibilities
- Execute ex vivo assays on diverse tissues collected from in vivo studies, perform analyses, and report results.
- Support ex vivo biological analysis (e.g., biomarker discovery) in collaboration with other IVTS scientists, Altos Hubs and cross-functional teams.
- Evaluate and implement new technologies and platforms to enhance the efficiency and quality of studies.
- Maintain detailed documentation of all studies in an electronic lab notebook to ensure data integrity and traceability.
- Collaborate effectively with the in vivo operation teams to enable execution of high quality in vivo studies.
- Collaborate with cross-functional teams, including Discovery Sciences, in vitro Pharmacology, Drug Metabolism and Pharmacokinetics, etc. to support the development and progression of therapeutic programs.
- Contribute to a team culture that promotes continuous improvement, ownership, professional growth, and inclusion.
Requirements
- Research Specialist experience requirements: Bachelors or Masters degree and 8+ years of industry experience.
- Scientist experience requirements: PhD in Molecular Biology, Biochemistry, Pharmacology or related field, with at least 4 years relevant industry experience.
- Extensive experience designing and executing biochemical and biophysical assays, including: Enzymatic assays, ELISAs, MSD, AlphaLISA, Western Blots, qPCR and ddPCR.
- Extensive experience with tissue processing methods, including extraction, quantification and QC of nucleic acids and proteins.
- Demonstrated ability to design and troubleshoot assays to support diverse therapeutic modalities (e.g., small molecules, biologics, gene therapies).
- Strong record of scientific productivity and the ability to independently design rigorous, reproducible, and generalizable experiments.
- Proficient in documenting and communicating results clearly (e.g., ELN, slide decks, team presentations).
- Strong collaboration and communication skills; ability to work effectively within cross-functional teams.
Qualifications
- Bachelors or Masters degree and 8+ years of industry experience as a Research Specialist.
- PhD in Molecular Biology, Biochemistry, Pharmacology or related field, with at least 4 years relevant industry experience as a Scientist.
- Extensive experience designing and executing biochemical and biophysical assays, including: Enzymatic assays, ELISAs, MSD, AlphaLISA, Western Blots, qPCR and ddPCR.
- Extensive experience with tissue processing methods, including extraction, quantification and QC of nucleic acids and proteins.
- Demonstrated ability to design and troubleshoot assays to support diverse therapeutic modalities (e.g., small molecules, biologics, gene therapies).
- Strong record of scientific productivity and the ability to independently design rigorous, reproducible, and generalizable experiments.
- Proficient in documenting and communicating results clearly (e.g., ELN, slide decks, team presentations).
- Strong collaboration and communication skills; ability to work effectively within cross-functional teams.