Research Specialist - Obal Lab
Position Responsibilities
Function as a specialist/technical expert in cell biology/ iPSC technology. Investigate and perform critical analysis of current literature to develop novel approaches to understand of pharmacological and toxicological disturbance of early cardiovascular development.
Conduct research either independently or in conjunction with other investigators. Induced pluripotent stem cell reprogramming and culture. Cardiomyocyte, endothelial, and smooth muscle cell differentiation using human iPSCs. Perform cardiomyocyte, endothelial cell, smooth muscle phenotype and molecular evaluation protocols. Extensive experience with cloning, gene-editing in iPSC. Subcutaneous injection of drugs in pregnant mice. Collect, Analyze and Summarize Data; Prepare Reports; Contribute to Manuscripts, Publications
Education Requirements
Master's degree in Molecular Biology, Cell Biology, Biomedical Sciences, Physiology, Pharmacology, or a related scientific field, or an equivalent combination of education and related experience.
Experience Requirements
A minimum of three years of related research experience. Demonstrated experience with induced pluripotent stem cell (iPSC) culture, maintenance, and differentiation. Demonstrated experience applying scientific principles to independently design, conduct, analyze, and interpret research studies. Demonstrated experience maintaining detailed research records and documentation. Demonstrated proficiency with scientific data analysis software and programming tools, including Microsoft Office, R, Python, and/or MATLAB. Demonstrated ability to manage multiple priorities, work independently, and meet project deadlines. Excellent organizational, written, and verbal communication skills.
Desired Qualifications
PhD or Master's degree in Molecular Biology, Cell Biology, Biomedical Sciences, Physiology, Pharmacology, or a related discipline. Five or more years of experience in iPSC biology, gene editing, and cardiovascular research. Experience with NIH-funded research projects, grant preparation, and manuscript development. First-author peer-reviewed publications in a relevant scientific discipline. Experience developing and maintaining IRB and/or IACUC protocols. Technical writing experience, including SOPs, protocols, reports, manuscripts, and grant submissions. Proficiency with human cell culture techniques, including iPSC reprogramming, maintenance, and differentiation. Experience with molecular biology techniques including PCR, gel electrophoresis, recombinant DNA methods, cloning, and gene editing. Experience with laboratory animal research and drug administration procedures. Experience supervising, training, or mentoring students, trainees, or research staff. Experience with advanced data analysis, machine learning applications, and scientific programming using R, Python, and/or MATLAB.