Research Scientist [PDL Lab]

About the role

The Massachusetts General Hospital Cancer Center’s Process Development Laboratory seeks a full-time Process Development Scientist I to support and advance its translational cell and gene therapy research platform.

Responsibilities

• Makes proficient intellectual contributions to scientific strategies of the group/lab and plays a leadership role by acting as subject matter authority in the field.
• Contributes to the design and execution of experiments and/or research projects.
• Exercises judgment in selecting methods and technologies to obtain results.
• Collaborates with external researchers and/or receives external project funding support.
• Presents results and prepares publications.
• Affords assistance to PI in the training and supervision of other staff.

Requirements

• Doctorate related field of study required.
• Previous Research experience (inclusive of graduate and postdoctoral experience) 5-7 years required.

Qualifications

• Experience: Previous Research experience (inclusive of graduate and postdoctoral experience) 5-7 years required.
• Licenses and Credentials: Experience: Previous Research experience (inclusive of graduate and postdoctoral experience) 5-7 years required.

Skills and Abilities

• Excellent research skills.
• Demonstrated evidence of specific scientific competence in field.
• Demonstrated broad knowledge of field.
• Evidence of potential for scientific creativity and original thought.
• Able to exercise independent judgment and leadership.
• Ability to contribute to publications.

Additional Job Details (if Applicable)

The successful candidate will contribute to the design, development, optimization, and clinical translation of novel manufacturing workflows poised for IND-enabling studies and early-phase clinical trials, while operating in a collaborative academic medical center environment.

Preferred Qualifications

• Demonstrated experience in cell and/or gene therapy research and process development.
• Hands-on experience working with primary human cells, preferably immune effector cells.
• Strong foundation in cell culture, molecular biology, and translational experimental design.
• Experience with CAR T-cell or immune effector cell manufacturing.
• Familiarity with CRISPR/Cas-based genome editing technologies.
• Experience with viral vector production or gene delivery platforms.
• Exposure to cGMP environments, IND-enabling studies, or regulated manufacturing settings.
• Experience with closed-system or automated manufacturing platforms.
• Prior experience contributing to regulatory documentation, technology transfer, or validation activities.