Research Scientist, Biologics Analytics

About the role

Vertex is seeking a talented Research Scientist to join a collaborative research team focused on Biologics discovery and optimization in Boston, MA. The group’s mission is to deliver next generation biologics and genetic therapies impacting several therapeutic areas. We are looking for a candidate with a strong desire to deliver innovative new medicines to patients in need. In this lab-based role, the ideal candidate is strongly experienced in LC-MS based analytical method development and characterization of biologics including antibodies and antibody-like scaffolds, bioconjugates, and lipid nanoparticles. The candidate should be independent, accustomed to taking initiative, and bring enthusiasm and intellectual curiosity to Vertex’s fast-paced research environment. At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

Responsibilities

• Work collaboratively amongst several therapeutic areas and modalities to provide detailed product characterization to support program advancement
• Develop, execute and optimize LC and MS-based methods for the characterization of proteins, antibodies, antibody-like scaffolds, bioconjugates, and lipid nanoparticles
• Serve as the subject matter expert for LC-MS based analysis of protein and lipid nanoparticles
• Collaborate towards developability/manufacturability assessment in support of product advancement
• Transfer of analytical methods and technical support
• Active participation in group and cross-disciplinary project team meetings

Skills

• Proficient in protein and lipid nanoparticle characterization by liquid chromatography and mass spectrometry
• Familiarity with instrument integration and scheduling tools
• Strong understanding of biologics and lipid nanoparticle manufacturing and critical quality attributes
• Track record of productivity
• Ability to work effectively with cross-functional teams and prioritize multiple programs
• Strong ownership, scientific curiosity, attention to detail, and commitment to technical excellence

Qualifications

• Ph.D. (or equivalent degree) in biochemistry or related disciplines and 0-3 years of relevant post-doctoral employment experience, or
• Masters Degree (or equivalent degree) in biochemistry or related disciplines and 8+ years of relevant employment experience

Pay

Pay Range $104,200 - $156,200. Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

Benefits

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Schedule

Flex Designation: On-Site Designated. In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility. Note: The Flex