Research Laboratory Tech Sr

Job posting number: #7368974. Posted: August 18, 2026. Application deadline: Open until filled.

About the role

The laboratory of Agnieszka Lukaszewicz, in the Department of Human Genetics at the University of Michigan Medical School, is seeking a highly motivated senior research laboratory technician. The laboratory studies germline de novo mutations, with a focus on:

• Spectrum of de novo structural and copy number variants at meiotic DNA double-strand breaks in mice and humans
• Determining molecular mechanisms driving de novo mutations in meiosis
• Determining the impact of structural variation at recombination hotspots on genome stability

This is an excellent position for a recent college graduate interested in gaining a few years of research experience before applying to graduate school. The position offers regular and direct hands-on training from a PI to help determine interest in pursuing a graduate degree. The role is heavily focused on laboratory research, with a smaller amount of effort devoted to lab management for laboratory support and maintenance.

Responsibilities

Experimental responsibilities:

• Designing and performing PCR assays
• Mouse husbandry
• DNA extraction, subcloning, and genotyping
• Library preparation for next-generation sequencing
• Fluorescence microscopy
• Data analysis using a variety of software programs
• Preparation of data for presentation
• Training of new lab members and functional supervision for undergraduate students

Non-experimental responsibilities:

• Purchasing of lab supplies and equipment as authorized
• Managing lab safety program and compliance with animal protocols
• Maintenance of lab equipment

Requirements

• Bachelor's degree in biology, genetics, or a related area of study
• 1 year of undergraduate wet lab research experience
• Willingness to work with mouse model system
• Experience with PCR assays
• Experience with DNA extraction
• Knowledge and understanding of laboratory safety protocols including biological and chemical safety
• Ability and motivation to learn new experimental approaches and safety protocols, and analyze and present data
• Excellent teamwork and communication skills

Qualifications (desired)

• 2 years or more of undergraduate laboratory experience
• Experience with mouse husbandry
• Experience with Western blotting
• Experience with research data analysis
• Experience in training students and others on lab safety and on the application of new techniques