Research Lab Specialist Senior
University of Michigan · Ann Arbor, MI · 1 wk ago
AnalystFull-time
About the Role
The Research Laboratory Specialist Senior will serve as the core operational, medical, and regulatory anchor for a large animal lab within Biomedical Engineering. This role oversees a small NHP colony, runs precursor-to-GLP sheep and pig studies, ensures strict compliance across regulatory bodies (USDA, IACUC, IBC, EHS), and manages controlled substance compliance. The position also involves writing comprehensive IACUC protocols, leading pre- and post-operative care for surgeries, training PhD students and assistants, and handling lab administration including supply logistics and financial forecasting.
Responsibilities
- Nonhuman Primate Colony Management
- Manage a small NHP colony, including day-to-day medical needs and coordination with veterinarians.
- Maintain detailed documentation of weight, food and water consumption, general hours, and medical care.
- Train new NHP for poling, chairing, and acclimatization to handling with junior assistants.
- Develop and adapt personalized training plans for individual NHP.
- Regulatory
- Monitor and ensure compliance with USDA, IACUC, IBC, EHS, and controlled substance protocols.
- Serve as the primary contact for regulatory inspections.
- Manage controlled drugs compliance under the PI’s license.
- Run precursor-to-GLP sheep and pig studies, monitoring animal health and coordinating with the pathology core.
- Write and edit full IACUC protocols for NHP, sheep, and pig, often for PIs new to large animal research.
- Train lab members in safety procedures, including PPE, chemical safety, fire safety, and biosafety.
- Write and update SOPs for lab procedures.
- Medical
- Lead approximately 1-2 NHP surgeries per year and 1 sheep or pig surgery monthly.
- Oversee pre-operative setup and post-operative recovery, including anesthetic induction, intubation, intraoperative sensor placement, vitals monitoring, and recovery.
- Administer medications via all routes (e.g., IV) in NHP and other large animals.
- Develop and fabricate novel methods for experimental procedures and improve existing techniques.
- Assist PhD students with medical procedures, including ultrasound-guided nerve blocks.
- Serve as the primary liaison for PIs conducting large animal experiments without their own lab.
- Management
- Supervise and train PhD students and lab staff on equipment operation, procedures, and techniques.
- Demonstrate technology and equipment capabilities, operations, and limitations.
- Directly manage and teach veterinary procedures to assistants, often pre-veterinary students.
- Assign and oversee lab service tasks.
- Administrative
- Organize lab supplies and associated finances.
- Order and monitor lab supplies using spreadsheets to ensure critical items are in stock.
- Maintain financial forecasting spreadsheets for personnel funding across multiple grants.
- Meet regularly with the research administrator for post-award management.
Required Qualifications
- Master’s degree and over 15 years of experience working with large animals in a laboratory setting, with at least half of that time independently managing an NHP lab.
- 10+ years of experience working with awake NHP, including training animals from scratch for pole and collar handling.
- Experience training inexperienced personnel to handle NHP.
- Served as the primary contact for a lab during USDA, IACUC, IBC, EHS, and controlled substance inspections for at least 5 years.
- Substantial experience writing and establishing SOPs for a large animal lab.
- Independently written full IACUC protocols to assist PIs.
- Assisted PIs with no prior large animal experience in obtaining protocol approvals and data collection.
- At least 3 years of experience working with large animals in a GLP facility.
- Proficient in ultrasound-guided nerve blocks and all methods of drug delivery in large animals, including awake IV.
- Can independently or with junior assistance complete pre-operative setup, including anesthetic induction, intubation, vitals sensor placement, and monitoring.
- Experienced in animal recovery and post-operative monitoring.
- Trained and supervised junior assistants on medical procedures involving large animals.
- Skilled in using internal financial spreadsheets for lab purchasing and financial projections.
- Served as the primary day-to-day contact for a research administrator monitoring accounts.
Benefits
- Generous time off.
- A retirement plan with two-for-one matching contributions and immediate vesting.
- Comprehensive health insurance options.
- Life insurance.
- Long-term disability coverage.
- Flexible spending accounts for healthcare and dependent care expenses.
- Maternity and Parental Leave.
Schedule
This is an onsite position requiring 5 days per week.