Research Fellow - Orthopedic Surgery - Sammarco lab

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans.

Benefits

• Medical: Multiple plan options.
• Dental: Delta Dental or reimbursement account for flexible coverage.
• Vision: Affordable plan with national network.
• Pre-Tax Savings: HSA and FSAs for eligible expenses.
• Retirement: Competitive retirement package to secure your future.

Responsibilities

The Sammarco Laboratory in the Department of Orthopedic Surgery at Mayo Clinic is seeking an outstanding and highly motivated Postdoctoral Research Fellow to join a growing research program investigating the cellular and molecular mechanisms that regulate bone and soft tissue regeneration. Our laboratory seeks to understand how fundamental cellular processes direct regenerative healing, with the long-term goal of translating these discoveries into therapies that improve musculoskeletal repair and functional recovery. Our research integrates molecular biology, regenerative biology, and advanced imaging to investigate fundamental mechanisms of tissue regeneration.

• Independently design, execute, troubleshoot, and interpret complex molecular, cellular, imaging, and animal-based studies addressing fundamental questions in musculoskeletal regeneration.
• Develop scientific hypotheses, optimize and establish new experimental approaches, critically evaluate data and the literature, and identify new research directions that advance the laboratory's mission.
• Generate high-quality, reproducible data using advanced molecular biology, cell biology, histology, imaging, and mouse-based techniques.
• Analyze complex datasets, prepare publication-quality figures, write first-author manuscripts, contribute to fellowship and grant applications, and present research at laboratory meetings and regional, national, and international scientific conferences.
• Contribute intellectually to the laboratory's research program by mentoring research staff and trainees, fostering scientific rigor and reproducibility, supporting collaborative projects, and helping shape the future direction of the laboratory.

Current areas of investigation include cellular metabolism, mitochondrial homeostasis and remodeling, reactive oxygen species (ROS) signaling, sensory nerve regulation of bone regeneration, cellular senescence, and the molecular pathways that distinguish regenerative healing from fibrosis.

Qualifications

• Must have a Ph.D., M.D., or equivalent doctoral degree. A Ph.D. in biology, molecular biology, biomedical sciences, developmental biology, regenerative biology, neuroscience, bioengineering, or a related field is preferred.
• Demonstrated strong record of scientific productivity through peer-reviewed publications reflecting the ability to independently conduct rigorous research.
• Extensive experience in molecular and cellular biology and the ability to independently design experiments, troubleshoot complex methodologies, and interpret findings within a broader biological context.
• Experience with mammalian cell culture, mouse models, histology, immunohistochemistry, microscopy, quantitative image analysis, and advanced molecular techniques is highly desirable.
• Excellent written and verbal communication skills, with demonstrated experience preparing publication-quality figures, writing scientific manuscripts, and presenting research to diverse scientific audiences.
• Experience writing fellowship applications or contributing to grant proposals is preferred.
• Scientific creativity, intellectual curiosity, exceptional organizational skills, and the ability to manage multiple concurrent projects.
• Highly self-motivated, capable of working independently within a collaborative multidisciplinary environment, and committed to the highest standards of scientific rigor, reproducibility, and integrity.
• Strong leadership and mentoring skills.

Applications submitted without a cover letter describing research interests, career goals, and motivation for joining the laboratory will not be considered.

Exemption Status: Exempt

Pay

$67,282 - $78,711/ year; Education, experience and tenure may be considered along with internal equity when job offers are extended.

Schedule

• Full Time
• Hours/Pay Period: 80
• Schedule Details: Varies