Research Biologist

(ID: 2026-3035) Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH). Benefits:100% Medical, Dental & Vision Coverage for EmployeesPaid Time Off (Including Holidays)Employee Referral Bonus401K MatchTuition reimbursement and professional development opportunitiesFlexible Spending Accounts:Healthcare (FSA)Parking Reimbursement Account (PRK)Dependent Care Assistant Program (DCAP)Transportation Reimbursement Account (TRN)Position OverviewAxle is seeking a Research Biologist to serve as a senior research scientist in the conduct and leadership of research focused on immunologic lung injury, using advanced molecular techniques — including next-generation sequencing, cell-free DNA and cell-free RNA analysis, and high-density proteomics platforms — to support early diagnosis of lung injury, disease monitoring, and personalized treatment for patients who have or are at risk of serious lung disorders. This role supports detection and analysis of novel molecular markers to help reduce patient morbidity and mortality from immunologic lung disease following human stem cell transplantation. A Master's degree in Biology, Immunology, or a relevant field is required, along with at least five years of relevant scientific experience, the ability to design experiments and analyze results with appropriate statistical analysis, and the ability to write methods and results sections for high-quality scientific publications.Field of StudyBiology, Immunology, or a relevant fieldSkillsAt least five (5) years of relevant scientific experienceAbility to perform next-generation sequencing, cell-free DNA analysis, cell-free RNA analysis, and high-density proteomics platform assays, as well as learn other assays as assignedAbility to design experiments to meet the requirements of the principal investigatorAbility to analyze results and present them with appropriate statistical analysisAbility to write methods and results sections for high-quality scientific publicationsDeliverablesWork products and documents related to performing experiments and procedures, including but not limited to cell-free DNA, cell-free RNA, and a variety of -omic platforms — Upon RequestWork products and documents related to recording and interpreting experimental research data — Upon RequestComputer-generated work, including preparing manuscript drafts for publication — Upon RequestWork products and documents related to providing reports of research activities — Upon RequestPreliminary reports related to budget and regulatory activities — Upon RequestStatement of Work DetailsServe as a Biologist and senior research scientist in the conduct and leadership of research focusing on immunologic lung injuryUse multiple advanced molecular techniques — including next-generation sequencing, cell-free DNA and cell-free RNA analysis, and high-density proteomics platforms — to support early diagnosis of lung injury, disease monitoring, and personalized treatments for patients who have or are at risk of serious lung disordersProvide detection and analysis of novel molecular markers to support reducing patient morbidity and mortality due to immunologic lung disease following human stem cell transplantationIdentify causative immunologic mechanisms (cells and molecules) in each patient to direct further therapeutic interventions related to autoimmune-associated lung injury after hematopoietic stem cell transplantationSupport the "Early Detection of Infectious and Noninfectious Lung Diseases Following Allogeneic Stem Cell Transplantation" protocol (001742-H) by performing single-cell sequencing and high-density proteomic analysis of blood and lung cells to help define mechanisms of altered lung function and identify patients at high risk of life-threatening lung injurySupport the "Quantitative Autoantibody Levels and Proteomic Endotypes in Myositis-Interstitial Lung Disease" study (B2B Award 1167415) by performing high-density proteomic assays (e.g., proximal extension assay) and quantitative autoantibody assays to characterize proteomic endotypes and identify trends in autoantibody levels and protein signatures in response to immunosuppressive therapySupport other research projects as assigned The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment-based age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.comDisclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individual’s assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location. Salary Range: $120,000 USD - $130,000 USD