Jobs · Engineering · Washington

Research Associate/Senior Research Associate, Protein Engineering

SystImmune · Redmond, WA · 1 wk ago
On-siteEngineering$60k–$85k/yrFull-time

Key Responsibilities

  • Design and generate display libraries with guidance from experimental and computational data. This includes library preparation and QC, NGS sequencing, and flow cytometry-based lead selection.
  • Culture engineered yeast for use in lead selection and sorting.
  • Construct/convert immune-based repertoires from immunized animal sources for use in both discovery and protein engineering campaigns.
  • Troubleshoot technical issues and implement solutions to optimize lead molecules, ensuring data quality and integrity throughout the discovery and optimization process.

Required Qualifications

  • BS or MS in immunology, biochemistry, molecular biology, structural biology, or a related field. Title and compensation commensurate with experience
  • 1+ year industrial drug development experience
  • 1+ years of hands-on experience in an aspect of display campaigns or genomics approaches in protein design or directed evolution projects
  • Demonstrated proficiency in one or more of the following workstreams: library design and generation, display-based selection, and assay development
  • Strong molecular biology background and experience. Library generation experience is a plus
  • Cell culture experience (bacterial, mammalian, and/or yeast) is required
  • Experience in FACS-based selection and sorting preferred
  • Excellent problem-solving skills, with the ability to troubleshoot technical issues and implement effective solutions
  • Outstanding organizational skills, attention to detail, and the ability to manage multiple projects simultaneously in a fast-paced environment
  • Strong communication and interpersonal skills, with the ability to collaborate effectively within multidisciplinary teams

Work Environment

  • The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job.
  • This individual will work in cell culture laboratory alongside other scientists and in a standard business office with desktop business equipment and a moderate noise level.

Physical Demands

  • While performing the duties of this job, the employee is regularly required to sit for long periods of time. This individual must be able to operate standard laboratory and business equipment.

Compensation and Benefits

  • The expected base salary range for this position is $60,000 - $85,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate’s level qualifications, experience, and skills.

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