Research Associate III / Associate Scientist - Chemistry

About the role

We are seeking a talented and motivated chemist to join our Discovery Chemistry team and contribute to the design and synthesis of DNA-encoded libraries (DELs). This hands-on position offers the opportunity to shape the company’s DEL-based lead discovery platform, working at the interface of chemistry, biology, and automation.

Responsibilities

• Design and validate novel DEL library builds.
• Develop and bring in new DNA-compatible chemical transformations that can widen the DEL chemical space.
• Construct DEL libraries to support the in-house library production efforts.
• Work with external partners to support our DEL synthesis and hit follow-up strategies.
• Engage in cross-functional team discussions that support DEL screening, data analysis, machine learning, and hit-optimization.
• Contribute to platform automation and technology development efforts.
• Present results, document workflows, and contribute to scientific and strategic planning within the Discovery Chemistry organization.

Requirements

• B.S. or higher in Chemistry, Biochemistry, or Medicinal Chemistry.
• 2–5 years of industrial experience (title determined by experience).
• Strong background in synthetic organic chemistry.
• Hands-on laboratory experience synthesizing DNA-encoded libraries.
• Familiar with the overall DNA-Encoded Library Technology workflow operations.
• Experience analyzing and purifying DNA-conjugates using common analytical tools (LCMS/HPLC).