Research Associate I, Early Research & Process Development

Location: Columbus, OH (100% Onsite) • Duration: 10-Month Contract

Responsibilities

• Maintain and scale up mammalian cell culture seed trains using aseptic techniques.
• Develop proficiency to maintain and become the primary superuser of the control software operation of Bioflo320 systems for small- and medium-scale (3L, 10L and 50L) recombinant protein productions.
• Take routine samples from ongoing productions and evaluate critical performance attributes.
• Perform daily management of consumables and waste streams, including buffer and tubing preparation.
• Participate in the maintenance, calibration and troubleshooting of CLD and USP instruments.
• Support upstream team members in experiment setup, execution, breakdown, and analytical sample submission.
• Assist in the proper documentation of experimental records.
• Present research findings in group meetings to team members and leadership.
• Coordinate weekly/monthly laboratory activities.
• Contribute to a safe, efficient, and effective team environment with personal accountability.

Education and Skills Requirements

• B.S. in Biomedical engineering, chemistry/chemical engineering, biology, biochemistry or related degree with 0-2-year related experience.
• Previous experience of mammalian cell culture techniques such as cell passaging, aseptic technique processing, transient transfection and cell culture harvest is desired.
• Experience in upstream techniques for production of biologics particularly antibody and/or viral vectors (AAV, Lenti-) production is a plus.
• Experience in basic biochemistry laboratory techniques such as qRT-PCR, SDS-PAGE, Western blot, ELISA, etc. is desired.
• Ability to think critically and demonstrate troubleshooting and problem-solving skills.
• Self-motivated with a strong sense of ownership in areas of responsibility and willingness to accept temporary responsibilities outside of initial job description.
• Comfortable in a fast-paced environment with minimal direction and able to adjust workload based upon changing priorities.
• Proven ability to successfully manage projects and timelines, organize/track complex information, prioritize accordingly, and the ability to quickly adjust to shifting priorities and demanding timelines when necessary.
• Excellent communication skills with the proven ability to build open and collaborative relationships and work effectively as a member of a multidisciplinary team.