Research Associate, Drug Discovery
General Proximity · San Francisco, CA · 2 wk ago
OTHRFull-time
About the role
We are seeking an experienced Research Associate to be a key member of our Platform/Drug Discovery Team. In this position, you will work in close conjunction with our Biology Team in the development of our core drug discovery technology and the generation of a completely novel class of therapeutics.
Responsibilities
- Designing and executing experiments independently or in collaboration with senior researchers
- Contributing to the development and optimization of experimental protocols and assays
- Preparation and handling of biological samples including mammalian cell cultures
- Performing advanced laboratory techniques and methodologies
- Data analysis and interpretation under the guidance of senior researchers
- Recording and organizing experimental data accurately and efficiently
Requirements
- BS or MS in Biology, Biochemistry, Molecular Biology, or a related field
- Deep understanding of small-molecule drug discovery and its relationship to human disease
- Top-notch written and oral communication skills
- Proficiency in:
- Mammalian cell culture, passaging/seeding cells, aseptic technique
- Molecular biology/cloning, PCR, and other common biology techniques like western blotting, flow cytometry, microscopy, and biochemical assays
- Assay development and optimization
Qualifications & Nice-to-Haves
- Industry experience is desirable, but the ability to work hard and learn fast is more important to us.
- Strong understanding of basic biological principles and laboratory techniques
- Strong problem-solving skills and the ability to work independently as well as part of a team
- Nice To Have:
- 2+ years of post-degree experience
- Experience with HTS and phenotypic cell-based assay development
- Transient/stable protein expression and purification, immunoprecipitation assays
- Experience working with CRISPR-Cas systems
- Familiarity with data analysis software (e.g., Prism) and statistical tools
- Familiarity with automatic, robotic dispensers, liquid handlers
- Prior experience on teams that have successfully advanced research to the clinic
Benefits
- Strong equity incentives
- Top tier medical, dental, and vision coverage + One Medical membership
- 401(k) retirement plans
- Education and health/fitness incentive programs
- Meditation retreats—do a ten-day Vipassana retreat without counting towards vacation days
- Reading budget! We will buy you books. 📚
- Located in the MBC BioLabs at 135 Mississippi Street, an entrepreneurial hub full of the best scientists and operators the Bay Area has to offer. Our lab is a very short walk from the 22nd St Caltrain Station and a number of wonderful restaurants and cafés.