Research Associate - Computational Immunology

Key Responsibilities

• Method and tool development
• Design, develop, test, and maintain computational tools for genomic and immunogenomic analyses
• Build and maintain reproducible, modular pipelines for high-throughput analyses
• Analyze and integrate large datasets across modalities
• Develop and manage analysis-ready databases and metadata frameworks
• Optimize computational workflows for high-performance computing and cloud environments
• Collaborate with wet-lab and clinical investigators
• Prepare figures, reports, and reproducible notebooks
• Present methods and results to multidisciplinary audiences

Minimum Qualifications

• M.S. degree in Computational Biology, Bioinformatics, Genomics, Computer Science, Biostatistics, or a related discipline plus three years of relevant experience
• OR Ph.D. in Computational Genomics, Computational Immunology, Computational Biology, Bioinformatics, Biostatistics, Computer Science, or a closely related field

Required Technical Expertise

• Demonstrated experience developing genomic analysis tools and pipelines and analyzing large-scale omics datasets
• Strong programming skills in Python and/or R; proficiency with scientific computing libraries and data structures
• Strong grounding in statistics for high-dimensional biology (e.g., regression models, multiple testing, experimental design, batch effects)
• Experience working in HPC/Linux environments, containerization, and job schedulers
• Ability to write clear documentation and produce publishable-quality analyses and visualizations

Preferred Qualifications

• Immunogenomics experience including TCR/BCR repertoire analysis, clonotype inference/annotation, diversity/selection metrics, and repertoire comparison across conditions
• Single-cell immune profiling (e.g., scRNA-seq / CITE-seq / scATAC-seq) and multi-omic integration
• Experience building and maintaining analysis databases and metadata schemas; familiarity with FAIR principles
• Prior contributions to open-source software, internal toolkits, or published methods papers

Core Competencies

• Strong analytical reasoning and scientific rigor; ability to debug complex pipelines end-to-end
• Excellent communication skills and ability to translate computational results for experimental and clinical collaborators
• High ownership, organization, and attention to detail; ability to manage multiple concurrent projects and deadlines
• Collaborative mindset with demonstrated ability to work in multidisciplinary teams

Pay

The annual base salary range for this position is $71,000 - $89,000.