Research Associate

About the role

The Mishra Lab at the Fralin Biomedical Research Institute at VTC in Roanoke, VA, is seeking a highly skilled Research Associate to support AHA-funded research programs focused on heart failure, cardiac remodeling, and cardiometabolic disease and perform Small-Animal Cardiovascular Surgery.

Responsibilities

• Performance of mouse cardiovascular surgeries, including transverse aortic constriction (TAC), myocardial infarction (MI), ischemia-reperfusion injury, and related surgical models of cardiovascular disease.
• Assist with animal colony management, post-operative monitoring, echocardiography, physiological phenotyping, tissue collection, and general laboratory operations.
• Maintain detailed records and be committed to high standards of animal welfare and scientific rigor.

Requirements

• Demonstrated expertise in mouse cardiovascular surgery, including TAC, MI, and related cardiac injury models.
• Experience with perioperative care, animal monitoring, anesthesia, analgesia, and survival surgery techniques.
• Experience with mouse handling, colony management, tissue harvesting, and animal research protocols.
• Ability to maintain detailed surgical and experimental records.
• Strong organizational skills and ability to work independently.
• Ability to stand, walk, bend and stoop for long periods of time.

Preferred Qualifications

• Experience with pressure-volume loop analysis, telemetry, or other in vivo cardiovascular measurements.
• Experience working in cardiovascular, heart failure, or translational research laboratories.
• Veterinary training or certification in laboratory animal science is highly desirable.