Radiochemistry Scientist I
Ratio Therapeutics · Boston, MA · 3 wk ago
On-siteAnalyst$105k–$125k/yrFull-time
Key Responsibilities
- Develop radiolabeling methods for small molecules and biologics
- Develop chromatographic methods to analyze and purify radiolabeled compounds (HPLC, GC, radio-TLC, etc.)
- Work to become the company’s Radiation Safety Officer
- Develop formulations suitable for use in animal and human studies
- Conduct in vitro assays to evaluate and optimize stability of radiolabeled compounds
- Translate radiolabeling methods to automated synthesis units
- Aseptically prepare radiolabeled products for preclinical studies
- Conduct quality control testing of products
- Maintain clear and accurate records and perform relevant lab maintenance and calibrations
- Stay up to date on current literature/radiolabeling methods
- Compose and follow standard operating procedures
- Interpret data, recognize aberrant results, and propose explanations and next steps
- Summarize data for reports, patents, and presentations
Qualifications
- Ph.D. in chemistry or related field is required
- Post-graduate radiochemistry experience is highly preferred (post-doc or otherwise)
- Working knowledge of organic and analytical chemistry
- Working knowledge of radiochemistry and competency working with radioactive materials
- Some publications in the field
- Ability to work well both independently and as part of a team
- Strong communication skills, including proficiency in English (both written and oral, as demonstrated by publication record)
- Demonstrated ability to prioritize, multitask, and troubleshoot problems
- Demonstrated ability to readily acquire new skills and techniques
- Must be able to lift 45 lbs. (handling of lead and tungsten vial/syringe shields)
Preferred Skills And Knowledge
- Experience with radiometal manual synthesis, including 111In, 68Ga, 64Cu, 90Y, 177Lu, and 225Ac among others
- Experience working in a CMC environment to help guide preclinical R&D strategy
- Experience with radiopharmaceutical manufacturing and testing for animal and/or human use
- In your CV or cover letter, please highlight isotope- and/or target-specific experience