RA-II/Sr. Research Associate, Protein Engineering
About the role
SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Bothell, WA and Princeton, NJ, specializing in innovative cancer treatments using bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). The company has multiple assets in clinical trials for solid tumor and hematologic indications and a robust preclinical pipeline. We are seeking a Research Associate II or Senior Research Associate to join our Protein Engineering team. This full-time onsite position in Bothell, WA is ideal for a highly motivated individual with strong molecular biology skills and a passion for scientific innovation, offering an opportunity to work in a dynamic environment focused on the development of novel therapeutic antibodies.
Responsibilities
- Perform routine and high-throughput molecular biology techniques, including library preparation, lentiviral vectors, PCR, restriction endonuclease digestion, Gibson Assembly, Golden Gate Assembly, bacterial transformations, and plasmid purification
- Execute BLI, SPR, and other binding analytical assays, ensuring accurate and reproducible data to support characterization of protein candidates
- Design mammalian expression plasmids and cloning strategies for proteins and multi-specific antibodies
- Support high-throughput protein analytic workflows with automation to enable rapid screening and characterization of constructs
- Maintain detailed records of experimental procedures and results in electronic lab notebooks
- Collaborate with team members to support cloning and construct generation for protein expression
- Assist in troubleshooting and optimizing molecular workflows to improve efficiency and throughput
- Manage multiple tasks and projects simultaneously in a fast-paced environment
- Maintain lab organization and inventory of reagents and supplies
Requirements
Bachelor’s or Master’s degree in Molecular Biology, Biochemistry, or a related field.
Qualifications
- Research Associate II: bachelor’s degree and 2+ years of industry experience
- Senior Research Associate: bachelor’s degree with 5+ years or master’s degree with 3+ years of industry experience
- 2+ years of hands-on lab experience in molecular biology techniques
Skills
- Experience with antibody-related workflows (plus)
- Liquid handler and automation experience (plus)
- Experience with next-generation sequencing workflows (plus)
- Strong organizational skills and attention to detail
- Ability to work independently and as part of a collaborative team
- Comfortable working in a dynamic environment with shifting priorities
Pay
The expected base salary range for this position is $70,000 - $90,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate’s level qualifications, experience, and skills. While most offers typically fall within the low to mid-point of the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise exceeds the requirements of the role.
Benefits
- 100% paid employee premiums for medical/dental/vision
- STD and LTD coverage
- 401(k) plan with a 50% company match of up to 3%
- Vesting schedule of only 5 years
- 15 PTO days per year
- Sick leave
- 11 paid holidays
- Additional benefits (MORE)
Schedule
Full-time onsite position in Bothell, WA.