R&D, Senior Scientist

About the role

Castle Biosciences is growing and seeking a full‑time R&D, Senior Scientist to work from the Friendswood, TX headquarters (with consideration for Pittsburgh, PA), starting October 30, 2026. At Castle, the mission is to empower healthcare providers and patients through innovative laboratory‑developed tests that reveal a person's unique biology to improve disease management and treatment decisions. The company fosters a culture of integrity, respect, trust, transparency, collaboration, and internal growth.

As a Senior Scientist you will drive the generation and communication of scientific evidence supporting Castle Biosciences' dermatologic oncology products. You'll collaborate across R&D, Medical Affairs, Marketing, Program Management, and Data Analytics to transform complex clinical and molecular data into meaningful insights that inform patient care and business strategy. Success requires a unique blend of scientific expertise, analytical rigor, strong communication skills, and the ability to thrive in a cross‑functional environment.

Responsibilities

• Data analysis, interpretation, and visualization
• Scientific communication through publications and presentations
• Cross‑functional collaboration and stakeholder engagement
• External scientific partnerships and Key Opinion Leader (KOL) engagement

Requirements

• PhD in life sciences or a master's degree with at least 5 years of industry experience
• Demonstrated interpersonal and organizational skills, as well as verbal and written communication skills (proficiency in English)
• Demonstrated independent writing experience in generating scientific deliverables (abstracts, posters, short oral presentations, etc.), with first‑hand experience in the publication process
• Demonstrated experience with clinical data analysis and statistics
• Demonstrated ability to manage timelines and function effectively in a fast‑paced environment
• Must be legally authorized to work in the United States; Castle Biosciences does not sponsor H‑1B visas, OPT, or employment‑related visas

Benefits

• Excellent annual salary + 20% bonus potential
• 20 accrued PTO days annually + 10 paid holidays
• 401(k) with 100% company match up to 6%
• Three health care plan options + company HSA contribution
• Company stock grant upon hire

Schedule

Typical work schedule is Monday through Friday (40+ hours per week), working from the Friendswood, TX headquarters or Pittsburgh, PA. Off‑hour work may be required to attend conferences, facilitate communication, and meet deadlines. Travel may be up to 10% of time.