Production Supervisor, HPC, Marrow

About the role

This position provides oversight of daily operations and training within Ossium Health’s Production group relating to the processing of donor tissue and HPC, Marrow. The Supervisor will oversee first‑shift staff involved in the intake, processing, and storage of donor tissue and bone marrow products for pre‑clinical and clinical use, ensuring a safe, controlled work environment and communicating site safety objectives and quality standards. The role reports directly to the Manager of Clinical Production. The source material is human marrow recovered from donated vertebral bodies; each donation is a gift honored by the team. Processing requires full gowning (over the head, face, hands, feet, and body) inside a cleanroom with limited breaks.

Responsibilities

• Oversee daily production of HPC, Marrow, including scheduling staff and troubleshooting processing issues
• Lead daily 1st‑shift huddles, escalating safety, quality, delivery, cost, and people issues during Tier 2 huddle
• Regularly meet with direct reports and escalate any concerns
• Perform or verify tasks in the production of HPC, Marrow as assigned
• Ensure necessary training is completed by all production staff
• Provide ongoing coaching and recognition of direct staff
• Review timesheets of direct reports
• Review bone marrow production batch records and associated documentation
• Perform allocation and authorization review for incoming donors and sample requests
• Ensure production activities comply with current Good Tissue Practices, AATB standards, and other relevant regulations
• Author or assist in drafting and revising departmental procedures
• Oversee cryopreservation and initial inventory of HPC, Marrow product and samples in freezers
• Process quality monitoring, including manipulation of databases, documents, and spreadsheets to support business reporting and communicate trends to production specialists
• Maintain production areas and records in an inspection‑ready state at all times
• Work with Sterile Processing and Equipment teams to monitor production equipment/tools, ensuring cleanliness, proper working order, and calibration/PM schedule compliance
• Interact with QA department to complete event reports, deviations, CAPAs, and change controls
• Interact with QC department to submit sample requests and prepare reports
• Interact with Management to provide updates, results, suggestions, and work‑area/process observations

Requirements

• High school diploma required
• 2+ years of experience managing people
• 4+ years of experience in manufacturing
• Knowledgeable with respect to manufacturing operations in a regulated environment
• Scientific aptitude and ability to clearly and thoroughly document all work on existing forms and records
• High level of attention to detail in both operations and documentation
• Excellent written and oral communication skills
• Capability to operate with a high level of organization and excellent time management in a dynamic startup environment
• Physical requirements: ability to work in a moderately noisy environment, around biohazardous materials and chemicals; majority of shift aseptically in a controlled environment with limited breaks requiring special gowning (over head, face, hands, feet, body); lift/push/pull/carry up to 50 lbs; sufficient manual dexterity, hand/finger coordination, wrist mobility/stability, and grip strength; regularly required to sit, stand, walk, squat, balance, climb, stoop, kneel, crouch, and reach; pre‑employment physical examination required after conditional offer

Qualifications

• BS or BA in biological sciences or equivalent (preferred)
• Knowledgeable with respect to aseptic techniques, clean‑room environment, cellular and tissue processing
• 2+ years aseptic processing or management experience (preferred)

Benefits

• Competitive salaries
• Stock options
• 401(k) matching
• Medical, dental, and vision coverage
• Four weeks of PTO accrued (vacation & sick time) annually + 11 company holidays
• Employer‑paid life insurance and long‑term disability
• Gym membership/recreational sports reimbursements

Schedule

Full‑time (40 hours per week) onsite in the Indianapolis facility. This is a salary, exempt role Monday through Friday, 6:00 a.m. to 2:30 p.m.; no nights and no rotating shifts. Occasional holiday and overtime work required: typically about one Saturday and one holiday per year, driven by donor recovery timing; overtime based on production processing needs. No weekend shifts currently; as we scale toward commercial production, weekend