Process Development Senior Scientist

Job Summary

Join Amgens Mission of Serving Patients At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission to serve patients living with serious illnesses drives all that we do. Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease, we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller, happier lives. Our award-winning culture is collaborative, innovative, and science-based. If you have a passion for challenges and the opportunities that lie within them, you'll thrive as part of the Amgen team.

About the Role

Process Development Senior Scientist

Responsibilities

• Work effectively with a diverse team of synthetic chemists, chemical engineers, and analytical chemists to develop scalable synthetic processes utilizing solid phase peptide synthesis.
• Drive technology innovation in solid-phase synthesis, purification, and characterization of synthetic peptides.
• Support cGMP manufacturing and technology transfer to external contract manufacturers.
• Achieve process performance through process understanding, modeling, and characterization.
• Contribute to drug substance development teams by providing experimental results, technical updates, documentation, data interpretation, recommendations, etc.
• Work cross-functionally to deliver regulatory documents and support regulatory filings.
• Serve as a technical expert and keep current in the field of solid phase peptide synthesis.
• Contribute to project advancement and studies within required deadlines.

Qualifications

• Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable] OR Masters degree and 3 years of scientific experience OR Bachelors degree and 5 years of scientific experience.
• Ph.D. in organic chemistry, biochemistry, or chemical engineering with expertise in synthetic peptide process development.
• Extensive hands-on expertise in the synthesis and purification of synthetic peptides produced by solid phase synthesis.
• Experience within the pharmaceutical/biotech industry developing solid phase peptide synthesis processes and scaling/transferring the process into GMP manufacturing.
• Familiarity with laboratory automation, data analysis and visualization techniques and tools.
• Track record of peer-reviewed publications and research presentations.
• Demonstrated ability to work within a dynamic and interdisciplinary environment to achieve results.
• Excellent written and verbal communication skills, ability to multitask, effectively plan and follow through on complex projects.