Process Development Senior Scientist
About the Role
In this vital role you will join our Drug Substance Technologies - Synthetics (DSTS) group at either our Thousand Oaks, CA or at our Cambridge, MA campus. Amgen's DSTS group within Process Development (PD) is responsible for the invention, development, and implementation of drug substance manufacturing processes and technologies to advance Amgen's exciting portfolio of synthetic and hybrid assets. Process chemists within our team apply their synthetic training to invent synthetic routes and chemical processes to support drug substance manufacturing from early to late-stage development. The successful candidate will be a highly motivated and team-oriented individual with a strong background in organic chemistry with a proven track record of scientific innovation and achievement.
Key Responsibilities
- Invent synthetic routes and develop safe, robust, and cost-effective processes to manufacture synthetic and hybrid drug substances
- Advance enabling technologies to accelerate pharmaceutical development and to improve sustainability and process efficiency
- Support cGMP manufacturing and technology transfer to our internal manufacturing facilities and external contract manufacturers
- Ensure process performance through process understanding, modeling and characterization
- Contribute to drug substance development teams by providing experimental results, technical updates, documentation, data interpretation, recommendations, etc.
- Work cross-functionally to deliver regulatory documents and support regulatory filings
- Serve as a technical expert and keep current in the field of organic and process chemistry
- Work effectively in a multi-disciplinary team of chemists, engineers and attribute scientists
- Work independently in advancing projects and studies within required deadlines
Basic Qualifications
- Doctorate degree PhD OR PharmD OR MD Chemistry completed by August 2026
- OR Master's degree and 3 years of Scientific experience
- OR Bachelor's degree and 5 years of Scientific experience
Preferred Qualifications
- Ph.D. in organic chemistry with a specialization in total synthesis, reaction methodology, mechanistic studies
- Post-doctoral experience in an academic laboratory or pharmaceutical/biotech industry
- Track record of peer-reviewed publications and research presentations
- Demonstrated ability to work within a dynamic and interdisciplinary environment to achieve results
- Excellent written and verbal communication skills, ability to multitask, effectively plan and follow through on complex projects
- A research summary included with CV is strongly encouraged
Benefits
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:
- A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans
- Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.
Additional Information
Sponsorship for this role is not guaranteed.