Principal Scientist, Systems and Disease Biology
BioSpace · Cambridge, MA · Yesterday
AnalystFull-time
Main Responsibilities
- Generating hypotheses on how targets, pathways, and cell types/states drive diseases (immunology, neurology, and oncology disease areas) by integrating multi-omics and multi-modal data, including real-world data and clinical metadata.
- Applying established analytical methods to understand disease and drug mechanisms.
- Developing intelligent agentic workflows that streamline the deployment of innovative algorithms and computational models.
- Leading projects involving internal experiment design and data analytics as well as outsourcing of established workflows and/or complex follow-up mechanistic assays (organoid, CRISPR, proteomics).
- Collaborating with academic, industry, and internal partners on method development and disease-focused scientific studies.
- Supporting high-profile presentations and publications.
- Mentoring interns and junior scientists, sharing knowledge, and fostering a collaborative research environment.
About You
- Ph.D. in systems biology, computational biology, biostatistics, or related quantitative field with proven experience in a relevant disease area (Immunology, Neurology or Oncology) OR PhD in biological sciences, biomedical sciences, immunology, neuroscience, oncology or in a related disease area and proven advanced track record of data analytics, ML/AI, or computational biology.
- At least 2 years of post-doctoral experience in relevant academic or industry roles.
- Hands-on experience in ML/AI and building or deploying agentic analysis workflows.
- Extensive hands-on experience and deep knowledge of multi-omics and/or multimodal data analysis, with ability to extract actionable interpretation and conclusions from the analysis.
- Track record of productivity, innovation, and impact (publications or patents).
- Excellent communication, organizational, interpersonal, and team skills; track record of success working collaboratively across disciplines.