Principal Scientist, Project Toxicologist

For our client, we are seeking a Principal Scientist, Project Toxicologist to join the team of a leader in the Pharmaceuticals & Biotech space. This role will serve as a key nonclinical safety expert on development project teams, helping guide scientific strategy for drug candidates from early assessment through regulatory interaction. The Principal Scientist will design and manage safety assessment programs, shape study approaches for complex scientific questions, and translate data into clear internal and external documentation. This position also partners closely with R&D stakeholders, regulatory teams, and external collaborators while mentoring scientists on nonclinical study design and oversight. Location: Remote - US based candidates only, no visa sponsorship available Compensation: $152,224 – $205,951 annually Responsibilities Serve as the toxicology and nonclinical safety representative on project teams Design and manage nonclinical safety assessment programs for drug development candidates Originate novel study designs to tackle complex scientific questions Evaluate and interpret data; author key internal governance and regulatory documents Collaborate with internal and external partners to advance R&D programs Mentor scientists on designing and overseeing nonclinical studies Engage with regulatory agencies on nonclinical safety topics Qualifications Doctorate degree (PhD, PharmD, or MD) with 2 years of experience as Project Team Representative (PTR) for nonclinical safety sciences Master’s degree with 5 years of PTR experience Bachelor’s degree with 7 years of PTR experience 6+ years of Pharmaceutical/Biotechnology industry experience post-PhD, including 4+ years as Nonclinical Safety PTR Extensive experience authoring regulatory documents and liaising with regulatory agencies Benefits Comprehensive employee benefits package including health, dental, and vision coverage Retirement and savings plan with company contributions Discretionary annual bonus program Stock-based long-term incentives Award-winning time-off plans Flexible work models where applicable Our client is an equal opportunity employer. We encourage you to apply even if you don’t meet every qualification—your background could be exactly what this team needs.