Principal Scientist, Oligonucleotide Analytical Chemistry

About the role

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade.

Responsibilities

• Develop and deploy robust analytical methods to support in-house oligonucleotide synthesis, including novel chemistries and conjugates
• Use advanced LC/MS-MS capabilities to fully characterize novel synthetic oligonucleotides and related species in low-and high-throughput settings
• Help design and manage key data pipelines
• Collaborate internally and externally, representing Oligonucleotide Discovery Analytical Chemistry on project teams
• Support analytical investigations, including root cause analysis, in collaboration with cross-functional teams
• Participate in hiring, mentoring and training of junior team members, ensuring knowledge transfer and capability development

Qualifications

• A BS degree with at least 8 years of relevant experience or an MS degree with at least 6 years of relevant experience in analytical chemistry or a related discipline (or equivalent)
• Two or more years of experience using high-resolution LC/MS(-MS) methodology in a biotechnology, pharmaceutical, or academic setting
• At least one year of experience utilizing modern mass spectrometry data analysis techniques, particularly as applied to biopolymers such as oligonucleotides, proteins, and/or glycans
• At least one year of experience in high-resolution LC/MS(-MS) method development and method troubleshooting

Bonus Information

• The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role.
• In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role.

Benefits

• Health care and other insurance benefits (for employee and family)
• Retirement benefits
• Paid holidays
• Paid vacation
• Paid caregiver/parental and medical leave

Why GSK?

We unite science, technology and talent to get ahead of disease together. GSK is a successful, growing company where people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.