Principal Scientist, Multiomics
About the role
and include that paragraph. - Responsibilities: The "You Will Be Responsible For" section with bullet points. We'll map to Responsibilities. - Requirements: The "Qualifications" section includes Education, Required, Preferred. Could map to Requirements and Qualifications? The instruction says use headings: About the role, Responsibilities, Requirements, Qualifications, Skills, Benefits, Pay, Schedule. So we need separate Requirements and Qualifications sections. We can split: Requirements = required minimum qualifications (education, experience, etc). Qualifications = preferred qualifications? Or we could treat Qualifications as the whole qualifications block. But we need both headings if content exists. Let's see content: Under "Qualifications" heading we have Education, Postdoctoral training preferred, Equivalent industry experience... Then "Required Minimum of 6 years..." etc. Then "Preferred Experience..." etc. So we can put Required items under Requirements heading, and Preferred items under Qualifications heading. Also there is a list of "Required Skills Preferred Skills:" which seems like a list of skills. That could go under Skills section. - Benefits: there is a Benefits section with details. - Pay: there is "The anticipated base pay range for this position is : $117,000.00 - $201,250.00". So we include Pay. - Schedule: not mentioned, so omit. We must not include boilerplate like EEO, accommodation, etc. Remove duplicated lines. We must preserve all substantive information. So we need to include all paragraphs and bullet points. We need to use- for any list of duties/requirements/benefits. For prose use
. We need to avoid repeating job title as heading. Not include Job ID. We must output only HTML fragment. Let's extract content. First, About Innovative Medicine paragraph(s): "At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit." Then later: "About Innovative Medicine Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at https://www.jnj.com/innovative-medicine" We need to preserve all substantive info; we can combine these paragraphs into About the role section. But we must not include navigation/legal/EEO etc. The first paragraph includes "Learn more at jnj.com". That's okay. Now Responsibilities: The bullet list under "You Will Be Responsible For Scientific Leadership & Platform Development" etc. There are subheadings: Scientific Leadership & Platform Development, Spatial Omics, Functional Genomics & MPRA, Cross-Platform Discovery. Each has bullet-like sentences. We'll treat each sentence as a list item. Let's extract: Scientific Leadership & Platform Development: - Lead the development, optimization, and deployment of advanced massively parallel reporter assays and in combination with single cell and spatial omics across discovery programs. - Design and implement innovative experimental workflows that integrate genetic perturbation, reporter assays, molecular profiling, and spatial analysis. - Evaluate, establish, and scale emerging technologies that enhance therapeutic pathway discovery, mechanism-of-action studies, and translational research. - Serve as a subject matter expert in spatial biology, functional genomics, and high-content genomics screening technologies. Spatial Omics: - Design and execute workflows involving in situ hybridization, microscopy, spatial transcriptomics, spatial proteomics, high-resolution imaging, and sequencing. - Develop and optimize spatial assays using platforms such as Bruker CosMx, 10x Genomics Visium, Xenium, and emerging technologies. - Apply spatial approaches to characterize cellular interactions, tissue architecture, disease mechanisms, and therapeutic responses. Functional Genomics & MPRA: - Develop and deploy massively parallel reporter assays (MPRAs) to investigate protein elements, disease-associated variants, transcriptional control mechanisms, and cell-state specific regulatory programs. - Design and execute pooled functional genomics studies, including CRISPR-based perturbation screens, barcode-enabled assays, and genetic screening workflows. - Lead experimental design for library construction, vector engineering, cellular model generation, assay validation, and screening campaigns. - Develop novel approaches that integrate perturbation, reporter activity, and transcriptional profiling within complex cellular systems. - Familiarity with Antibody structure and Biologics Discovery is highly preferred. Cross-Platform Discovery: - Build workflows that connect functional perturbation data with spatial phenotypes and tissue-level biology. - Partner with computational scientists to develop data standards, quality-control frameworks, and scalable analytical pipelines. - Collaborate with platform and therapeutic area scientists to translate multiomic findings into actionable biological insights and therapeutic hypotheses. Now Requirements (required qualifications): Education: PhD in Genetics, Genomics, Molecular Biology, Systems Biology, Human Biology, Bioengineering, Computational Biology, or a related discipline. Postdoctoral training is preferred. Equivalent industry experience with a strong record of scientific achievement will also be considered. Required Minimum of 6 years of biotechnology or pharmaceutical industry experience, or equivalent experience in highly technical translational research environments. Demonstrated scientific leadership with a strong record of publications, presentations, patents, or major technology contributions. Deep expertise in at least one of the following domains, with demonstrated experience working across both: - Spatial omics and molecular imaging technologies - Functional genomics, pooled screening, and massively parallel reporter assays (MPRAs) Proven experience in experimental design, assay development, technology optimization, and platform deployment. Experience generating and interpreting complex multiomics datasets. Ability to work effectively across biology, technology, computational science, and therapeutic area teams. Strong written, verbal, and presentation skills. Demonstrated ability to apply innovative approaches to address complex biological questions. Now Qualifications (preferred): Preferred Experience with spatial transcriptomics, spatial proteomics, single-cell genomics, or multimodal profiling technologies. Experience developing or applying MPRAs, CRISPR screens, Perturb-seq, pooled screening technologies, or regulatory genomics approaches. Familiarity with genomics library design, barcode-based assays, viral vector systems, and cell engineering. Experience with programming and data analysis in R and/or Python. Knowledge of neuroscience, oncology, immunology, or translational research applications. Experience managing multiple collaborations, external partners, and technology evaluations. Ability to serve as a scientific bridge between experimental and computational teams. Now Skills: There's a line: "Required Skills Preferred Skills: Big Data Management, Critical Thinking, Data Reporting, Data Savvy, Drug Discovery Development, Molecular Diagnostics, Organizing, Pharmaceutical Microbiology, Problem Solving, Product Knowledge, Project Reporting, Project Schedule, Research Proposals, Scientific Research, Standard Operating Procedure (SOP), Standard Scientific Processes and Procedures, Strategic Thinking, Sustainability" We can treat as Skills section list. Now Benefits: The Benefits section includes many bullet points. We'll list each as
- .
Benefits list:
- Vacation –120 hours per calendar year
- Sick time - 40 hours per calendar year; for employees who reside in the State of Colorado –48 hours per calendar year; for employees who reside in the State of Washington –56 hours per calendar year
- Holiday pay, including Floating Holidays –13 days per calendar year
- Work, Personal and Family Time - up to 40 hours per calendar year
- Parental Leave – 480 hours within one year of the birth/adoption/foster care of a child
- Bereavement Leave – 240 hours for an immediate family member: 40 hours for an extended family member per calendar year
- Caregiver Leave – 80 hours in a 52-week rolling period
- Volunteer Leave – 32 hours per calendar year
- Military Spouse Time-Off – 80 hours per calendar year
Also there is a line: "For additional general information on Company benefits, please go to: - https://www.careers.jnj.com/employee-benefits" That's a link; we can include as a paragraph maybe.
Now Pay: "The anticipated base pay range for this position is : $117,000.00 - $201,250.00". We'll put in
. Now we need to ensure we don't include boilerplate like EEO, accommodation, etc. Remove those paragraphs. Also remove duplicated lines like "Learn more at jnj.com" appears twice? We have one in first paragraph and later "Learn more at https://www.jnj.com/innovative-medicine". Keep both? They are not duplicated exactly; but we can keep both as they are substantive. Now produce HTML. Structure:
About the role
... paragraphs ...
Responsibilities
- ... ...
Requirements
- ... ...
Qualifications
- ... ...
Skills
- ... ...
Benefits
- ... ...
For additional general information on Company benefits, please go to: https://www.careers.jnj.com/employee-benefits
Pay
The anticipated base pay range for this position is : $117,000.00 - $201,250.00
We need to ensure we didn't miss any substantive info: The initial paragraph about Johnson & Johnson belief etc. Also the sentence "As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit." Should be included. Also the line "Job Function Discovery & Pre-Clinical/Clinical Development Job Sub Function Biological Research Job Category Scientific/Technology All Job Posting Locations: Cambridge, Massachusetts, United States of America, Spring House, Pennsylvania, United States of America" This is metadata; we can fold into a shortor drop. The instruction says do NOT put Job ID / requisition numbers as headings — fold minor metadata into a short
or drop it. So we can include a short paragraph with that info. Let's include after About the role maybe a
containing: Job Function: Discovery & Pre-Clinical/Clinical Development; Job Sub Function: Biological Research; Job Category: Scientific/Technology; Locations: Cambridge, MA; Spring House, PA. Now ensure we didn't include any boilerplate like EEO etc. The posting includes after Qualifications: "Johnson & Johnson is an Equal Opportunity Employer..." etc. Remove that. Also remove the accommodation lines. Now check for any duplicated lines