Principal Scientist, Lab Platform Disruptive Technologies

About the role

This role is based out of our Cambridge, MA facility and involves leading the development and deployment of next-gen lab-based experimental technologies to enable rapid, data-driven biologics discovery.

Responsibilities

• Develop and mature rapid, quantitative and high-throughput lab-based capabilities for biologics hit identification and optimization
• Build and execute a technology platform roadmap for arrayed and pooled technologies, from proof-of-concept through widespread program adoption
• Partner effectively with computational protein engineering and data science groups toward efficient, integrated next-gen discovery workflows
• Drive capability improvements in data richness, speed, throughput
• Lead a talented team of lab-based scientists
• Realize and maximize program impact of emerging technologies
• Collaborate effectively across geography and reporting lines
• Establish rigorous benchmarks (e.g. throughput, speed, reproducibility, data quality) and success criteria

Qualifications & Experience

• PhD in Biochemistry, Bioengineering, Chemical Biology, or related field with 7+ years directly relevant industry experience; MS or BS with 12+ years industry experience
• Experience developing large-scale, high throughput quantitative experimental methods for biologics discovery
• Proven leadership track record
• Deep hands-on expertise in one or more of: Quantitative pooled binding assays (10k+ sequences), Rapid and high throughput advanced endpoint assays (e.g. cell-based function, stability, localization, etc), Lab-on-chip technologies and protein arrays, Microfluidics