Principal Scientist, Discovery Separation Sciences
for section headings. Use - for any list of duties/requirements/benefits, and
for prose. Remove boilerplate: cookie/navigation/legal/EEO/equal-opportunity/scam-warning, duplicated lines, application instructions. Also remove "Current Employees apply HERE Current Contingent Workers apply HERE", "US And Puerto Rico Residents Only", "Our company is committed to inclusion..." etc. Also remove "Requirements As an Equal Employment Opportunity Employer..." etc. Also remove "Search Firm Representatives Please Read Carefully..." etc. Also remove "Employee Status Regular Relocation: Domestic VISA Sponsorship No Travel Requirements 10% Flexible Work Arrangements Not Applicable Shift Not Indicated Valid Driving License No Hazardous Material(s) Standard lab reagents Job Posting End Date 09/28/2026 A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date. Requisition ID:R417735". Also remove "The salary range for this role is $176,200.00 - $277,300.00 This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs. The successful candidate will be eligible for annual bonus and long-term incentive, if applicable. We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits." We need to keep salary range and benefits info. Also keep "You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting." That's application instruction; we should remove application instructions. So remove that line.
We need to preserve all substantive information: Position Overview, Primary Responsibilities (with bullet points), Education, Required Experience And Skills, Preferred Experience And Skills, Required Skills, Preferred Skills, Benefits, Pay (salary range). Also maybe "Relocation: Domestic VISA Sponsorship No Travel Requirements 10% Flexible Work Arrangements Not Applicable Shift Not Indicated Valid Driving License No Hazardous Material(s) Standard lab reagents" is metadata; we can fold into short p or drop. Probably drop as minor metadata.
We need sections: About the role (maybe from Position Overview). Responsibilities (Primary Responsibilities). Qualifications (Education + Required Experience And Skills + Required Skills?). Skills (Preferred Skills?). Benefits. Pay. Possibly Schedule not present, so omit.
We must not create sections with filler. Ensure each heading has content.
We'll produce HTML like:
About the role
Position Overview ...
Responsibilities
- ...
...
Qualifications
Education ...
Required Experience And Skills ...
Required Skills ...
But maybe better to split: Education, Required Experience, Required Skills as separate sections? The instruction: prefer a few substantive sections over many thin ones. Could combine Education+Required Experience+Required Skills into Qualifications. Preferred Experience And Skills and Preferred Skills could be under Preferred Qualifications.
But we need to preserve all info; we can include them as paragraphs under Qualifications.
Benefits: we have benefits description.
Pay: salary range.
Let's extract content.
Position Overview paragraph: "We are seeking an accomplished scientist and leader to join Discovery Chemistry as a Principal Scientist within the Boston Separation Sciences group. The successful candidate will provide scientific leadership and operational oversight for purification and analytical chromatography capabilities supporting drug discovery programs across multiple modalities, including small molecules, peptides, targeted protein degraders, and emerging therapeutic formats. This role requires deep technical expertise in both HPLC and SFC chromatography and demonstrated experience supporting a broad range of purification workflows, including high-throughput library purification, singleton purification, chiral separations, and analytical support for medicinal chemistry programs. The role combines laboratory leadership, scientific expertise, capability development, people management, and cross-functional collaboration to ensure the delivery of high-quality purification and analytical support to project teams. The Principal Scientist will contribute to the advancement of Separation Sciences capabilities through the implementation of innovative technologies, development of scientific talent, optimization of workflows, and partnership with colleagues across Discovery Chemistry and adjacent functions. The individual will serve as a recognized subject matter expert while contributing to project, departmental, and capability strategies that enhance the effectiveness and impact of drug discovery efforts."
Primary Responsibilities: It lists several bullet-like sentences but not actual bullet list. We need to convert to - . The text: "Primary Responsibilities May Include Scientific Leadership and Laboratory Delivery Serve as a recognized subject matter expert in purification and separation sciences, providing scientific leadership and contributing to purification and analytical activities that enable Discovery Chemistry programs through the delivery of high-quality compounds, analytical data, and scientific recommendations.Provide technical leadership and expertise in chromatographic purification, analytical separations, impurity isolation, and related technologies, while guiding resolution of complex scientific and operational challenges.Foster a culture of scientific excellence, operational efficiency, safety, and quality throughout laboratory operations. Capability Development and Innovation Champion and implement innovative technologies, laboratory informatics platforms, LIMS solutions, automation-enabled purification workflows, and digital capabilities that enhance the effectiveness, efficiency, and impact of Separation Sciences capabilities.Establish best practices, drive continuous improvement initiatives, and contribute to capability roadmaps aligned with Discovery Chemistry priorities. People Leadership and Talent Development Recruit, manage, mentor, and develop scientists and laboratory staff, building both technical expertise and leadership capability across the organization.Foster a collaborative, inclusive, and high-performing environment that supports employee development, succession planning, and scientific excellence. Cross-Functional Collaboration and Influence Partner closely with Medicinal Chemistry, Process Chemistry, Analytical Sciences, Automation, Informatics, IT, and other research functions to support project progression and capability development.Serve as a trusted scientific partner to project teams, contributing purification and analytical expertise to project strategy and departmental initiatives. Operations and Infrastructure Leadership Partner in laboratory operations, instrumentation strategy, capital planning, and implementation of automation and digital solutions that improve scientific productivity.Partner with Facilities, Procurement, Engineering, IT, and external vendors to ensure reliable laboratory operations, regulatory compliance, and continuous capability advancement. External Scientific Engagement Maintain awareness of emerging technologies and scientific advances in separation sciences and chromatography, contributing to our company's scientific reputation through publications, presentations, collaborations, and external engagement."
We need to split into logical items. Could treat each heading (Scientific Leadership..., Capability Development..., People Leadership..., Cross-Functional Collaboration..., Operations..., External Scientific Engagement) as items. We'll create
- for each.
Education: "Minimum Requirement Ph.D. in Chemistry, Analytical Chemistry, Pharmaceutical Sciences, Chemical Engineering, or a related scientific discipline with a minimum of 8 years of relevant industrial experience in a pharmaceutical, biotechnology, or related drug discovery research environment. Or M.S. in Chemistry, Analytical Chemistry, Pharmaceutical Sciences, Chemical Engineering, or a related scientific discipline with 10-12 years of relevant industrial experience in a pharmaceutical, biotechnology, or related drug discovery research environment. Or B.S. in Chemistry, Analytical Chemistry, Pharmaceutical Sciences, Chemical Engineering, or a related scientific discipline with 12-15 years of relevant industrial experience in a pharmaceutical, biotechnology, or related drug discovery research environment."
Required Experience And Skills: "Extensive experience in chromatographic purification and analytical separations supporting drug discovery programs, with expertise in HPLC, uHPLC, LCMS, SFC, and preparative chromatography technologies.Demonstrated experience supporting multiple therapeutic modalities, including small molecules, peptides, targeted protein degraders, and other emerging modalities.Experience with high-throughput experimentation (HTE), high-throughput and singleton purification workflows, laboratory automation, and analytical support within a Discovery Chemistry environment.Demonstrated ability to provide scientific leadership, influence technical direction, and deliver results through a laboratory-based scientific capability, including scientific leadership in chromatography, separation sciences, analytical chemistry, or related drug discovery capabilitiesExperience implementing new technologies, laboratory informatics platforms, LIMS solutions, automation-enabled purification workflows, digital workflows, instrumentation, and process improvements.Experience managing, mentoring, and developing scientific staff, with strong communication, collaboration, and organizational skills.Demonstrated commitment to safety, quality, and operational excellence."
Preferred Experience And Skills: "Track record of cross-functional and cross-site scientific leadership, capability deployment, technology transfer, and successful collaboration across Discovery Chemistry sites, scientific disciplines, and research organizations.Experience partnering with IT, Informatics, Automation, Facilities, Procurement, and external vendors to develop and advance scientific capabilities.Experience with laboratory capital planning, laboratory build-out, infrastructure strategy, or management of scientific instrumentation portfolios.Publications, presentations, patents, or other evidence of external scientific engagement and professional visibility."
Required Skills: list: "Chromatography, High-Performance Liquid Chromatography (HPLC), High-Throughput Experimentation (HTE), Liquid Chromatography-Mass Spectrometry (LC-MS), Organic Synthesis, Project Leadership, Scientific Leadership, Separation Sciences, Supercritical Fluid Chromatography (SFC)". Could be a list.
Preferred Skills: "Current Employees apply HERE Current Contingent Workers apply HERE" but that's application instruction; we should drop. Actually "Preferred Skills" section includes "Current Employees apply HERE Current Contingent Workers apply HERE". That's not a skill; it's application instruction. So we should drop that line. There's no other preferred skills listed. So we may omit Preferred Skills section entirely because no real content.
Benefits: "We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits."
Pay: salary range: "$176,200.00 - $277,300.00". Also mention bonus etc. We'll keep that.
We need to avoid repeating job title as heading. Already not.
We need to output only HTML fragment.
Let's craft.
We'll have sections:
About the role
Position Overview ...
Responsibilities
- Serve as a recognized subject matter expert in purification and separation sciences, providing scientific leadership and contributing to purification and analytical activities that enable Discovery Chemistry programs through the delivery of high-quality compounds, analytical data, and scientific recommendations.
- Provide technical leadership and expertise in chromatographic purification, analytical separations, impurity isolation, and related technologies, while guiding resolution of complex scientific and operational challenges.
- Foster a culture of scientific excellence, operational efficiency, safety, and quality throughout laboratory operations.
- Champion and implement innovative technologies, laboratory informatics platforms, LIMS solutions, automation-enabled purification workflows, and digital capabilities that enhance the effectiveness, efficiency, and impact of Separation Sciences
for prose. Remove boilerplate: cookie/navigation/legal/EEO/equal-opportunity/scam-warning, duplicated lines, application instructions. Also remove "Current Employees apply HERE Current Contingent Workers apply HERE", "US And Puerto Rico Residents Only", "Our company is committed to inclusion..." etc. Also remove "Requirements As an Equal Employment Opportunity Employer..." etc. Also remove "Search Firm Representatives Please Read Carefully..." etc. Also remove "Employee Status Regular Relocation: Domestic VISA Sponsorship No Travel Requirements 10% Flexible Work Arrangements Not Applicable Shift Not Indicated Valid Driving License No Hazardous Material(s) Standard lab reagents Job Posting End Date 09/28/2026 A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date. Requisition ID:R417735". Also remove "The salary range for this role is $176,200.00 - $277,300.00 This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs. The successful candidate will be eligible for annual bonus and long-term incentive, if applicable. We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits." We need to keep salary range and benefits info. Also keep "You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting." That's application instruction; we should remove application instructions. So remove that line. We need to preserve all substantive information: Position Overview, Primary Responsibilities (with bullet points), Education, Required Experience And Skills, Preferred Experience And Skills, Required Skills, Preferred Skills, Benefits, Pay (salary range). Also maybe "Relocation: Domestic VISA Sponsorship No Travel Requirements 10% Flexible Work Arrangements Not Applicable Shift Not Indicated Valid Driving License No Hazardous Material(s) Standard lab reagents" is metadata; we can fold into short p or drop. Probably drop as minor metadata. We need sections: About the role (maybe from Position Overview). Responsibilities (Primary Responsibilities). Qualifications (Education + Required Experience And Skills + Required Skills?). Skills (Preferred Skills?). Benefits. Pay. Possibly Schedule not present, so omit. We must not create sections with filler. Ensure each heading has content. We'll produce HTML like:
About the role
Position Overview ...
Responsibilities
- ... ...
Qualifications
Education ...
Required Experience And Skills ...
Required Skills ...
But maybe better to split: Education, Required Experience, Required Skills as separate sections? The instruction: prefer a few substantive sections over many thin ones. Could combine Education+Required Experience+Required Skills into Qualifications. Preferred Experience And Skills and Preferred Skills could be under Preferred Qualifications. But we need to preserve all info; we can include them as paragraphs under Qualifications. Benefits: we have benefits description. Pay: salary range. Let's extract content. Position Overview paragraph: "We are seeking an accomplished scientist and leader to join Discovery Chemistry as a Principal Scientist within the Boston Separation Sciences group. The successful candidate will provide scientific leadership and operational oversight for purification and analytical chromatography capabilities supporting drug discovery programs across multiple modalities, including small molecules, peptides, targeted protein degraders, and emerging therapeutic formats. This role requires deep technical expertise in both HPLC and SFC chromatography and demonstrated experience supporting a broad range of purification workflows, including high-throughput library purification, singleton purification, chiral separations, and analytical support for medicinal chemistry programs. The role combines laboratory leadership, scientific expertise, capability development, people management, and cross-functional collaboration to ensure the delivery of high-quality purification and analytical support to project teams. The Principal Scientist will contribute to the advancement of Separation Sciences capabilities through the implementation of innovative technologies, development of scientific talent, optimization of workflows, and partnership with colleagues across Discovery Chemistry and adjacent functions. The individual will serve as a recognized subject matter expert while contributing to project, departmental, and capability strategies that enhance the effectiveness and impact of drug discovery efforts." Primary Responsibilities: It lists several bullet-like sentences but not actual bullet list. We need to convert to- . The text: "Primary Responsibilities May Include Scientific Leadership and Laboratory Delivery Serve as a recognized subject matter expert in purification and separation sciences, providing scientific leadership and contributing to purification and analytical activities that enable Discovery Chemistry programs through the delivery of high-quality compounds, analytical data, and scientific recommendations.Provide technical leadership and expertise in chromatographic purification, analytical separations, impurity isolation, and related technologies, while guiding resolution of complex scientific and operational challenges.Foster a culture of scientific excellence, operational efficiency, safety, and quality throughout laboratory operations. Capability Development and Innovation Champion and implement innovative technologies, laboratory informatics platforms, LIMS solutions, automation-enabled purification workflows, and digital capabilities that enhance the effectiveness, efficiency, and impact of Separation Sciences capabilities.Establish best practices, drive continuous improvement initiatives, and contribute to capability roadmaps aligned with Discovery Chemistry priorities. People Leadership and Talent Development Recruit, manage, mentor, and develop scientists and laboratory staff, building both technical expertise and leadership capability across the organization.Foster a collaborative, inclusive, and high-performing environment that supports employee development, succession planning, and scientific excellence. Cross-Functional Collaboration and Influence Partner closely with Medicinal Chemistry, Process Chemistry, Analytical Sciences, Automation, Informatics, IT, and other research functions to support project progression and capability development.Serve as a trusted scientific partner to project teams, contributing purification and analytical expertise to project strategy and departmental initiatives. Operations and Infrastructure Leadership Partner in laboratory operations, instrumentation strategy, capital planning, and implementation of automation and digital solutions that improve scientific productivity.Partner with Facilities, Procurement, Engineering, IT, and external vendors to ensure reliable laboratory operations, regulatory compliance, and continuous capability advancement. External Scientific Engagement Maintain awareness of emerging technologies and scientific advances in separation sciences and chromatography, contributing to our company's scientific reputation through publications, presentations, collaborations, and external engagement." We need to split into logical items. Could treat each heading (Scientific Leadership..., Capability Development..., People Leadership..., Cross-Functional Collaboration..., Operations..., External Scientific Engagement) as items. We'll create
- for each.
Education: "Minimum Requirement Ph.D. in Chemistry, Analytical Chemistry, Pharmaceutical Sciences, Chemical Engineering, or a related scientific discipline with a minimum of 8 years of relevant industrial experience in a pharmaceutical, biotechnology, or related drug discovery research environment. Or M.S. in Chemistry, Analytical Chemistry, Pharmaceutical Sciences, Chemical Engineering, or a related scientific discipline with 10-12 years of relevant industrial experience in a pharmaceutical, biotechnology, or related drug discovery research environment. Or B.S. in Chemistry, Analytical Chemistry, Pharmaceutical Sciences, Chemical Engineering, or a related scientific discipline with 12-15 years of relevant industrial experience in a pharmaceutical, biotechnology, or related drug discovery research environment."
Required Experience And Skills: "Extensive experience in chromatographic purification and analytical separations supporting drug discovery programs, with expertise in HPLC, uHPLC, LCMS, SFC, and preparative chromatography technologies.Demonstrated experience supporting multiple therapeutic modalities, including small molecules, peptides, targeted protein degraders, and other emerging modalities.Experience with high-throughput experimentation (HTE), high-throughput and singleton purification workflows, laboratory automation, and analytical support within a Discovery Chemistry environment.Demonstrated ability to provide scientific leadership, influence technical direction, and deliver results through a laboratory-based scientific capability, including scientific leadership in chromatography, separation sciences, analytical chemistry, or related drug discovery capabilitiesExperience implementing new technologies, laboratory informatics platforms, LIMS solutions, automation-enabled purification workflows, digital workflows, instrumentation, and process improvements.Experience managing, mentoring, and developing scientific staff, with strong communication, collaboration, and organizational skills.Demonstrated commitment to safety, quality, and operational excellence."
Preferred Experience And Skills: "Track record of cross-functional and cross-site scientific leadership, capability deployment, technology transfer, and successful collaboration across Discovery Chemistry sites, scientific disciplines, and research organizations.Experience partnering with IT, Informatics, Automation, Facilities, Procurement, and external vendors to develop and advance scientific capabilities.Experience with laboratory capital planning, laboratory build-out, infrastructure strategy, or management of scientific instrumentation portfolios.Publications, presentations, patents, or other evidence of external scientific engagement and professional visibility."
Required Skills: list: "Chromatography, High-Performance Liquid Chromatography (HPLC), High-Throughput Experimentation (HTE), Liquid Chromatography-Mass Spectrometry (LC-MS), Organic Synthesis, Project Leadership, Scientific Leadership, Separation Sciences, Supercritical Fluid Chromatography (SFC)". Could be a list.
Preferred Skills: "Current Employees apply HERE Current Contingent Workers apply HERE" but that's application instruction; we should drop. Actually "Preferred Skills" section includes "Current Employees apply HERE Current Contingent Workers apply HERE". That's not a skill; it's application instruction. So we should drop that line. There's no other preferred skills listed. So we may omit Preferred Skills section entirely because no real content.
Benefits: "We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits."
Pay: salary range: "$176,200.00 - $277,300.00". Also mention bonus etc. We'll keep that.
We need to avoid repeating job title as heading. Already not.
We need to output only HTML fragment.
Let's craft.
We'll have sections:
About the role
Position Overview ...
Responsibilities
- Serve as a recognized subject matter expert in purification and separation sciences, providing scientific leadership and contributing to purification and analytical activities that enable Discovery Chemistry programs through the delivery of high-quality compounds, analytical data, and scientific recommendations.
- Provide technical leadership and expertise in chromatographic purification, analytical separations, impurity isolation, and related technologies, while guiding resolution of complex scientific and operational challenges.
- Foster a culture of scientific excellence, operational efficiency, safety, and quality throughout laboratory operations.
- Champion and implement innovative technologies, laboratory informatics platforms, LIMS solutions, automation-enabled purification workflows, and digital capabilities that enhance the effectiveness, efficiency, and impact of Separation Sciences