Principal Research Scientist II, Process Chemistry

About the Role

AbbVie Process Chemistry is responsible for the chemical development of AbbVie's clinical candidates. We are looking for a highly motivated Principal Research Scientist II who can make scientific contributions and develop strategies, timelines, and key activities across drug substance modalities, including small molecules.

Responsibilities

• Participate and/or lead project teams associated with drug substance process development and characterization.
• Develop and characterize drug substance processes in the laboratory and translate them to scalable processes.
• Proactively advise and share knowledge and expert opinions with subordinates, peers, and senior management.
• Mentor staff in troubleshooting strategic and experimental issues.
• Author and review key regulatory documents, laboratory data, technical memos, and reports.
• Identify and nurture ideas for continuous improvement activities and initiatives within the department.
• Set project strategies, define project responsibilities and timelines, develop control strategies, provide leadership in a matrixed team setting, and develop robust processes for cGMP manufacturing.

Qualifications

• BS (16+ years); MS (14+ years) or PhD (8+ years) in Chemistry or allied field, with 8+ years of previous work experience in a pharmaceutical laboratory setting.
• Proven scientific leadership; strong interpersonal and communication skills for facilitating collaborations and a demonstrated ability to lead cross-functional process development teams.
• Experience with GMP drug substance manufacturing and process development.
• Experience in managing and developing scientific leaders.
• Strong understanding of modern organic chemistry, mechanistic theory, process development, control strategy development, and regulatory starting material strategies.

Key AbbVie Competencies

• Interacts well with diverse groups within the function and maintains strong working relationships with internal and external collaborators to enable higher performance.
• Learns fast, grasps the "essence," and can change course quickly where indicated.
• Raises the bar and is never satisfied with the status quo.
• Creates a learning environment, open to suggestions and experimentation for improvement.
• Embraces the ideas of others, nurtures innovation, and manages innovation to reality.

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance, and 401(k) to eligible employees. This job is eligible to participate in our long-term incentive programs.