Principal Research Scientist I Eng

About the role

The successful engineering candidate will play a key role in the R&D Process Engineering function. The core deliverable of R&D Process Engineering is to develop robust manufacturing processes and advance innovative technologies using strong engineering fundamentals. The ideal candidate will have significant prior reaction development and scale-up experience with demonstrated examples of scale up of small molecules and/or biologics from lab to pilot or production scales. The candidate is also expected to lead the identification and development of novel approaches and technologies to enhance process development efficiency and commercialization.

Responsibilities

• Develop robust manufacturing processes, supporting assets through all phases of development.
• Participate in and/or lead project teams towards development and characterization of new small and large molecule assets. Establish, communicate, and execute research plans.
• Develop commercial ready manufacturing processes in the laboratory and demonstrate the processes in the pilot plant.
• Set project strategies, define project responsibilities and timelines, and provide leadership in a matrixed team setting.
• Address challenging problems with chemical and biochemical reactions, separations, and/or isolations using demonstrated expertise in reaction kinetics, transport phenomena, and mathematical modeling.
• Develop and apply process analytical technologies and data-rich experimentation tools to build appropriate reaction and process understanding via model-guided experimentation.
• Build data-driven and knowledge-driven models to facilitate successful scale-up and tech transfer.
• Author and/or review technical documents summarizing process development efforts and contribute to regulatory filings.
• Exhibit a collaborative nature in identifying process challenges on a wide range of projects and communicate findings and recommendations effectively by multi-disciplinary interactions with organic chemists, analytical chemists, process development engineers, pilot plant engineers, drug product development scientists, program managers, and regulatory affairs specialists.
• Author publications and present at scientific conferences.

Qualifications

• BS, MS, or PhD in Chemical/Bio Engineering or a related field and 14+ (BS), 12+ (MS), or 6+ (PhD) years of relevant industrial experience.
• Job level will be commensurate with academic and/or industrial work experience.
• Ph.D. candidates with pertinent research exposure are also encouraged to apply.
• Candidates are expected to have a strong background in chemical engineering and the proven ability to demonstrate their skills in this field.
• The candidate is expected to demonstrate the ability to solve difficult technical problems and champion new technologies to achieve project goals.
• The candidate is required to be a strong team player and demonstrate scientific leadership, possessing effective oral and written communication skills for facilitating collaborations and leading cross-functional process development teams.