Principal Operations Scientist: Histopathology

About the role

Principal Operations Scientist - Permanent - Newark, CA Drive scientific excellence at the intersection of histopathology, digital pathology, and translational research as a key leader in advancing breakthrough therapies. Proclinical is seeking a Principal Operations Scientist specializing in histopathology to join a dynamic team in Newark, CA.

Responsibilities

• Provide scientific leadership across histopathology, translational biomarker, and tissue-based research workflows, including assay development, validation, scientific interpretation, and process optimization.
• Collaborate with internal scientific teams and customers to design, plan, and monitor execution of histopathology, biomarker, and tissue-based research programs.
• Apply digital pathology, whole-slide imaging, image-management platforms, and quantitative image-analysis tools to support scientific interpretation and project execution.
• Develop, optimize, or support image-analysis workflows using Visiopharm or comparable digital pathology platforms, as appropriate to project needs.
• Perform or oversee quantitative tissue analysis, biomarker scoring, cell phenotyping, and spatial tissue assessments as required by assigned programs.
• Coordinate scientific project execution, priorities, timelines, resource needs, and cross-functional handoffs within the assigned scope.
• Develop, maintain, and improve SOPs, quality systems, operational controls, and scientific best practices that support consistent project delivery.
• Serve as a primary scientific and technical resource for customers, collaborators, and internal stakeholders.
• Participate actively in customer project discussions, study design, technical scoping, and project-planning conversations.

Requirements

• Ph.D. in Pathology, Biomedical Sciences, Biology, Bioengineering, or a related field.
• Experience in histopathology, translational biomarker research, or closely related tissue-based translational research.
• Strong knowledge of tissue-based assays, pathology techniques, biomarker analysis, and scientific interpretation of histopathology data.
• Demonstrated experience leading scientific projects or small cross-functional teams through technical guidance, influence, and project coordination.

Skills

• Experience with digital pathology, whole-slide imaging, image analysis, Visiopharm, or comparable platforms.
• Expertise in immunohistochemistry (IHC), immunofluorescence (IF), multiplex imaging, or spatial biology.
• Experience supporting proposal development, study design, or other customer-facing scientific activities.

Pay

$180 000.00 - $200 000.00/Annum