Principal Manufacturing Associate

Join Immatics and shape the future of cancer immunotherapy, making a meaningful impact on the lives of patients with cancer. As the global leader in precision targeting of PRAME, we offer an innovative environment, collaborative culture, and the opportunity to contribute to therapies with global impact.

About the role

We are seeking a Principal Manufacturing Associate to provide direct leadership and oversight for the on-the-floor operations of cell therapy manufacturing in a cGMP environment.

Location: 13203 Murphy Road Suite 100, Stafford, TX 77477
Schedule: 7:00am - 3:30pm, Monday to Friday, on-site
Reports to: Manufacturing Manager

Requirements

• Biomanufacturing Technology Associate of Applied Science Degree, Biomanufacturing Technology Level 2 Certificate, or equivalent; or an Associate degree in Biology, Biochemistry, Biotechnology, Biomanufacturing, or another related field.
• 7+ years of cell therapy manufacturing experience, or 4+ years of cell therapy manufacturing experience combined with lead or supervisory experience.

Responsibilities

• Knowledge and adherence to cGMP requirements.
• Provide leadership, guidance, and necessary training to staff in alignment with cGMP requirements and established procedures.
• Provide instruction to facilitate workflow, shift activities, and shift exchange ensuring all activities are completed as assigned.
• Maintain a safe and controlled work environment.
• Support deviation workflow, including initiating, investigating, and troubleshooting deviations and unexpected events.
• Serve as backup for manufacturing associates for daily manufacturing processes.
• Review executed batch records and documents.
• Coordinate with the Training Department to include training needs on the manufacturing schedule.
• Communicate clearly with outgoing and incoming shift Leads and Managers to disseminate all relevant information.
• Collaborate with the MSAT/PD teams to transfer new projects into GMP.
• Develop or update internal policies, procedures, or steps; identify and escalate risks; communicate changes and plan for execution.
• Lead routine team meetings and huddles.
• Work productively and participate in a highly creative and fast-paced environment.

Work Environment

• cGMP clean room spaces and facilities (~80% of work hours).
• Grade A/B/C/D GMP environment with associated facility noise levels.
• Routine handling of blood components and occasional exposure to temperatures between -196°C and 40°C, liquid nitrogen, liquid nitrogen vapor, dry ice, and carbon dioxide.
• Lifting: raising or lowering objects up to 25 lbs.
• Ability to push or pull carts and gas tanks on rolling wheels (approximately 50 lbs.).
• Must pass a color blindness evaluation and assessment of vision abilities required for this position.

Benefits

• Comprehensive health, dental, and vision insurance at competitive rates.
• 4 weeks of vacation granted up front each year (prorated for first and last year of employment).
• 12 company-paid holidays.
• 7 days of sick time.
• 100% employer-paid life insurance up to 1x annual salary (up to $100,000).
• 100% employer-paid short- and long-term disability coverage.
• 401(k) with immediate eligibility and company match:
  • 100% match up to 3% of base salary for the first two years of employment.
  • 4% match for years 2-3 of employment.
  • Up to 5% match from the fourth year onward of continued employment.
• Partially paid parental leave for eligible employees.
• Additional voluntary employee-paid benefits, including accident, hospital indemnity, critical illness insurance, identity theft protection, and pet insurance.