Principal Enterprise Architect

About the role

The Enterprise Architect will help shape and implement Myriad Genetics’ next-generation technology stack, aligning architecture decisions with business growth, operational scale, and life sciences priorities. This role requires a pragmatic architecture leader who has successfully delivered modern enterprise platforms in healthcare, diagnostics, biotech, or life sciences environments.

Responsibilities

• Enterprise Architecture Strategy: Define architecture strategies, principles, standards, and roadmaps that connect Myriad’s life sciences business priorities to scalable technology execution.
• Architecture Design & Governance: Design, review, and guide business, application, data, integration, security, and technology architectures across enterprise initiatives, ensuring alignment to platform strategy and long-term reuse.
• Technology Evaluation & Decision Support: Lead buy vs. build vs. hybrid evaluations for strategic capabilities, balancing business fit, technical fit, cost, risk, scalability, compliance, and speed to value.
• Next-Gen Platform Implementation: Provide architecture leadership for implementation of iPaaS, MDM, DXP, IAM, API management, cloud, data platforms, automation, intelligent document processing, and AI-enabled capabilities.
• Discovery & Stakeholder Alignment: Facilitate discovery, capability assessments, current-state/future-state mapping, and decision alignment across business, product, engineering, security, data, and operations teams.
• Executive Communication: Prepare concise recommendations, roadmaps, trade-off analyses, and decision summaries for senior leadership and governance forums.
• Business Case & Value Realization: Partner with business and finance teams on investment justification, total cost of ownership, ROI modeling, and measurable business outcomes.
• Delivery Partnership: Work closely with product, program, engineering, and vendor teams to keep implementation aligned to architecture intent, business outcomes, quality, timelines, and constraints.
• Modernization & Reuse: Identify opportunities to simplify, consolidate, modernize, and reuse technology capabilities across the enterprise.
• Risk, Security & Compliance: Identify technical, security, compliance, data, and operational risks and recommend practical mitigation strategies.
• Architecture Artifacts: Create practical artifacts such as capability maps, target-state diagrams, integration patterns, reference architectures, decision records, and roadmaps.
• Standards & Best Practices: Promote architecture standards, patterns, and practices that enable secure, consistent, and effective use of enterprise platforms.

Qualifications

• Education: Bachelor's degree in Computer Science, Information Systems, or a related field; Master's degree preferred.
• Experience: Minimum of 10 years in IT architecture, including 5+ years in healthcare, diagnostics, biotech, or life sciences, with demonstrated experience implementing modern enterprise platforms.
• Skills: Strong architecture, analysis, communication, and stakeholder alignment skills; practical experience with enterprise architecture frameworks such as TOGAF; exposure to cloud, APIs, data platforms, Salesforce, Oracle, laboratory systems, portals, and SaaS ecosystems.
• Life Sciences Knowledge: Strong understanding of healthcare, diagnostics, biotech, or life sciences operating models, including regulatory, privacy, data, and interoperability considerations such as HIPAA, PHI, and FHIR.
• Technologies: Hands-on implementation exposure to iPaaS, MDM, DXP, IAM, API management, cloud, data platforms, intelligent document processing, AI-enabled workflows, and related integration and automation patterns.

About the Team

You will be working with the Office of the CTO within Myriad Genetics’ Enterprise Architecture team. Our team partners across business and technology functions to shape enterprise strategy, guide major platform decisions, and deliver scalable digital transformation. We are focused on life sciences innovation, modern platform enablement, and architecture practices that improve provider, patient, commercial, operational, and data capabilities.