Principal Data Scientist (AI-assisted Clinical Development)

The Opportunity

The IA Principal Data Scientist plays a pivotal role in building and deploying AI/ML-powered digital solutions that transform how we develop medicines. You will partner closely with product managers, software engineers, and UX researchers to design, test, and scale statistical capabilities that unlock actionable insights from clinical, operational, and real-world data.

• Design and productize the execution of simulation studies to evaluate innovative trial designs and statistical frameworks
• Translate complex scientific and operational considerations into software requirements that productize model development and usage, collaborating with domain experts to productize the validation of assumptions and result interpretation
• Independently drive exploratory analysis of complex clinical, biomarker, and operational data to extract insights and develop predictive models
• Develop scalable, reproducible pipelines for data processing, model training, evaluation, and deployment in regulated environments
• Optimize model performance, ensure algorithmic fairness, proactively mitigate bias or drift in deployed systems, and develop evaluation approaches for algorithms including generative AI (GenAI) components
• Co-lead the architectural design of ML and GenAI systems supporting traceability, compliance, and explainability
• Partner with software engineering, product, UX, and science teams to integrate models into real-world user applications
• Contribute to scientific leadership by publishing and presenting novel methodologies in high-impact venues, both internal and external
• Serve as a best-practice resource for statistical modeling strategies, code quality, and responsible AI principles
• Lead or co-lead cross-functional data science efforts that impact portfolio strategy and delivery