Principal, Biostatistician
Position Summary
The Principal, Biostatistician will own the statistical and quantitative work that connects clinical evidence to Roivant's key decisions across its pipeline. This role involves direct involvement in trial datasets and translating rigorous analysis into actionable recommendations.
Responsibilities
Work directly in ongoing and completed clinical trial datasets to identify efficacy signals, safety patterns, and subgroup effects that inform go/no-go and commercialization decisions.
Build rigorous statistical analyses from scratch: mixed-effects models, longitudinal models, Bayesian frameworks, subgroup analyses, and sensitivity analyses across Roivant's pipeline assets.
Monitor emerging safety signals and unexpected findings in real time across ongoing studies; surface and contextualize them for leadership before they become surprises.
Pressure-test clinical assumptions: challenge endpoint choices, scrutinize statistical analysis plans, and flag where the data does not support the narrative.
Execute focused 1-5 day analytical sprints on the highest-priority questions from Roivant and Vant leadership.
Qualifications
Advanced degree in biostatistics, statistics, epidemiology, or a closely related quantitative field; direct experience in clinical trial statistics strongly preferred.
Hands-on fluency with clinical trial data; you have worked directly in patient-level datasets, not just read summaries of analyses others ran.
Deep command of statistical methods used in clinical development: mixed-effects models, longitudinal and repeated-measures analyses, Bayesian approaches, multiplicity adjustment, and sensitivity analyses.
Familiarity with clinical trial design and regulatory statistical frameworks (ICH E9, estimands, SAP development).
Track record of translating rigorous analysis into decisions; your numbers have changed something.
Able to present complex statistical findings clearly to non-technical audiences, including CEO-level stakeholders.
Intensely curious, resourceful, and motivated; you run toward hard, ambiguous problems.
Context
Roivant is preparing to become the next breakout commercial-stage biotech, with the commercialization of brepocitinib, IMVT-1402, and mosliciguat. This role ensures that an unusually rigorous understanding of the clinical evidence that defines each market exists, carrying real ownership, direct exposure to senior leadership, and a trajectory that can serve as a foundation for future senior roles across the platform.
Compensation & Benefits
This is a full-time position.
The role offers meaningful equity participation and a comprehensive company-sponsored benefits package.
Base salary will be determined during the interview process and will vary based on multiple factors, including prior experience, relevant expertise, current business needs, and market conditions.
The expected base salary will generally be between $130,000 to $220,000 per year at commencement of employment, but the final salary offered may be outside this range based on individual circumstances.
This position is at-will and Roivant reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance and business and market conditions.
Company
Roivant Sciences provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws. We will not accept unsolicited resumes nor outreach from agencies. Please do not send agency resumes to our website or Roivant Sciences and affiliated employees. Thanks!