Principal Applied AI Engineer

Redesign Health is a global venture and applied technology firm focused on building next-generation healthcare companies. We manage venture capital and venture buyout strategies, each powered by an AI operating system and team of leading technologists, entrepreneurs, and investors. Our venture capital strategy backs exceptional founders at the earliest stage—often before an idea is fully formed—and provides first institutional capital and strategic leverage through exit. Our venture buyout strategy partners with proven management teams through control investments and delivers outsized value by rewiring core products and workflows with AI. Since inception in 2018, Redesign and our portfolio companies have touched the lives of more than 15 million patients, raised over $1.5 billion from premier institutional, sovereign, and strategic investors, and built partnerships with marquee healthcare organizations worldwide.

About The Team

Redesign's technology practice combines a frontier applied AI lab with deep healthtech investing expertise. Members of the practice have founded companies worth more than two billion dollars and built systems that serve hundreds of millions of patients, providers, and expert users, including NASA, CIA, and 90% of the Fortune 500. The practice is responsible for Redesign's technical investments, supports founders with architect-level guidance and over a million dollars in AI and cloud credits, and builds the agentic operating system at the core of our business. We help every team at Redesign use that system to become more technical, creative, and self-sufficient. We believe everyone is a builder, and that AI can let exceptional operators turn their expertise into software at the speed of thought.

We are a team of founders and researchers, musicians and astrophysicists, caregivers and friends. We prize analytical rigor, intellectual humility, and a drive to learn, build, and teach. We have been working on language models since before they were large, but we still reinvent ourselves every day as technology changes how we work and collaborate. We believe that AI will do more good for humanity in healthcare than anywhere else.

About The Role

We're hiring an ambitious, self-initiated, product-minded Principal Applied AI Engineer to build the agentic workflows that power Redesign’s most important decisions: the founders we back, the concepts we pursue, the people we hire, the investors we work with, and the healthcare partners we support. You will turn messy, high-judgment business workflows into scalable, self-learning systems that compound the firm’s impact. You will ship with the ownership of a founder and the judgment of an investor. You keep current with frontier AI research and retool your tradecraft every day. You will join a global team of former founders, architects, and research scientists in a high-leverage role. Your peers will be among the most senior technical and business leaders at the firm. You may hire and manage additional engineers as needed.

Responsibilities

• Redefine healthcare investing as a technical discipline. Design and ship AI systems to unlock one of the world's densest and highest-impact repositories of healthtech venture knowledge. Embed with our investment, talent, and global development teams to solve problems in deep research, alternative people and organizational data, and human-agent interaction. Constantly raise the bar on the level of technical sophistication we embody and offer to our founders, portfolio, and healthcare partners.
• Push the frontier of applied AI. Build durable, long-horizon agents, combine complex human judgment with context engineering and self-improving feedback loops, and constantly invent things that didn't exist yesterday. Publish, open-source, and share what you learn across our portfolio, healthcare partners, and the broader research community.
• Raise the technical bar across the company. Use the work you ship to teach the organization what AI can do, contribute reusable patterns back to our core systems, and help teammates and portfolio companies understand how to build differently in an AI-native world.
• Create global patient impact. As a technologist-investor, source, assess, inspire, and close exceptional founders, then support them in building enduring, transformative health technology companies that serve millions of patients and providers worldwide.

Requirements

• 10+ years in a senior technical role at a major venture-backed startup, frontier AI lab, or investment firm. Bonus points for founding a company and building a product from 0-1, or for meaningful time inside a VC or similar.
• Expert in Python and/or TypeScript with millions of lines of code written and reviewed. Proficient with modern agent frameworks (Lang* / Deep Agents, the Anthropic Agent SDK, or similar) and have shipped systems on top of them in production.
• Built or materially modified the harness around an agent: custom tools or agentic CLIs, MCP servers, durable and sandboxed execution, observability, and self-learning loops. Built stateful, long-horizon agentic systems well beyond basic RAG, and have wrestled with evals, context engineering, and failure modes that emerge when models sit in front of real business users. Bonus points for a pre-LLM background in machine learning, knowledge graphs, semantic search, or for having built CRM-like intelligence products such as enterprise RevOps or recruiting software.
• Completely reinvented your workflow around AI. Built sophisticated systems on top of coding agents like Claude Code (skills, MCPs, custom harnesses for development and code review) and have hardly written code by hand in over a year.
• Technology is one of your passions, but you find deep meaning in another pursuit: a creative or athletic outlet, a family business, or service.

Qualities

• Relentless, startup-native technologist with a high tolerance for ambiguity and an even higher speed of execution.
• Obsessive about building products people love. Where others see requirements, you see people trying to do difficult work with imperfect tools. You earn their trust by working alongside them and go to unreasonable lengths to ensure what you build creates outsized impact.
• Architect interfaces for agents as deliberately as most engineers architect interfaces for humans. You think about tools, context, memory, evals, and failure recovery as product surfaces.
• Drawn to the messy human systems where data, relationships, and expertise are combined to predict the future. Ideally, you have worked inside an investment firm, built software for one, or spent enough time around investors and operators to understand how they work.
• Outstanding executive presence and can skillfully elicit critical information about what to build. You help nontechnical leaders understand "the art of the possible" and they trust you because you deliver for them.
• Thrive in a group of passionate, talented, diverse, and low-ego individuals because these kinds of people love working with you.
• Deeply motivated to transform global healthcare and see technology as the true calling through which you can better the world.
• Accomplished something most people haven't: started a company, won an international academic award, shipped a product loved by many, performed music around the world, or overcome difficult circumstances to succeed. You have dedicated your life to excellence in your craft.

Company Values

• Patients are waiting: Work with the urgency that patients deserve.
• AI sets the floor: Nothing short of what AI in expert hands can deliver; taste and judgment own the last mile.
• Stack the team: Talent density is our greatest asset; raise the bar with every hire.
• Trust people, challenge ideas: Assume good intent; never shy from rigorous debate.
• Sweat your craft: Take pride in your work; seek feedback to continuously improve.
• Go beyond: Your role, comfort zone, and expectations for what’s possible.
• Be the partner you want: High integrity, responsive, and genuinely invested in shared success.
• No shortcuts: Patient safety, clinical standards, and partner trust above all.

Pay & Schedule

You will work on a hybrid schedule from our offices in New York, San Francisco, or Bengaluru. We target world-class talent and compensate accordingly, with packages containing a mix of cash and fund equity.