Postgraduate Scholar - Seibold/Moore Lab

About the role

The Seibold and Moore Laboratories are seeking a passionate and highly motivated Postgraduate Scholar to join our cutting-edge, NIH-funded research team. Our laboratories bring together an interdisciplinary group of experts in cell biology, skin and molecular biology, alongside experts in computational biology, bioinformatics, and statistical genetics. Our research focuses on unraveling the complex pathobiological mechanisms underlying atopic dermatitis, food allergy, asthma, and other allergic diseases. The goal of our work is to identify and characterize pathobiological subtypes (i.e. endotypes) of allergic disease, and to determine the genetic, environmental, and immunological factors that drive disease development, progression, and treatment response.

Responsibilities

• Perform transcriptomic profiling of longitudinal skin samples collected from a multi-center birth cohort study to determine inflammatory endotypes of atopic dermatitis in infancy and whether these patterns of dysregulation contribute to the development of food allergy in infancy.
• Identify common patterns of allergic disease development in early life and describe the differences in molecular and cellular development of the skin that underlie the atopic march and other patterns of allergic disease development and resolution.
• Use whole genome- and RNA-seq data to identify eQTLs that influence early life skin expression and longitudinal skin development among allergic disease groups.

Requirements

• A Ph.D. or strong background in computational biology, bioinformatics, or biostatistics.
• Experience in analyzing bulk and single cell RNA-seq data, performing differential expression analyses, cell type deconvolution, eQTL and transcriptome wide association studies (TWAS).
• Expertise in cell or skin biology, molecular biology, and/or immunology.
• Relevant laboratory skills including human primary tissue culture, immune cell phenotyping, scRNA-seq, and other genomic/genetic characterization techniques.

Qualifications

• Strong ability to interpret and analyze complex data.
• Capability to clearly communicate findings.
• Commitment to collaboration and working closely with both internal teams and external research collaborators.

Skills

• Excellent problem-solving skills.
• Ability to work independently and collaboratively.
• Strong communication and interpersonal skills.

Benefits

Comprehensive Medical Coverage, Health Savings Accounts (HSA), Flexible Spending Accounts (FSA), Paid Time Off, Dental & Vision Plans, Retirement Savings, Tuition Reimbursement, Child Care Assistance, Loan Forgiveness, Disability & Life Insurance, Voluntary Benefits, Wellness Incentives, Exclusive Discounts, and Volunteering Opportunities.

Pay

$62,232.00 - $75,564.00

Schedule

On-site, full-time position.