Postdoctoral Research Fellow

Duties And Responsibilities

• Design and conduct in vivo efficacy studies to test gene editing strategies and/or compounds in FD mice.
• Perform downstream analyses, including RNA/protein quantification, splicing analysis, and histological assessments.
• Lead the development and optimization of therapeutic delivery and molecular assays.
• Collaborate with internal and external researchers and contribute to mentorship of junior lab members.
• Prepare manuscripts, present findings at scientific meetings, and contribute to grant applications.

Qualifications

• EDUCATION: Minimum Required: Doctoral Degree
• Experience Required: Doctoral degree
• PREFERRED: Ph.D. in neuroscience, molecular biology, genetics, or a related field.

Desired Skills And Competencies

• Molecular biology techniques including DNA, RNA, and protein isolation and manipulation (RT-PCR, qRT-PCR, western blotting)
• Good understanding of genetic methodologies, with experience in cloning, CRISPR/Cas genetic editing techniques, genomic sequencing
• Some level of cell culture experience, including cell lines generation, transfection/transduction, selection, propagation, preservation, and phenotypic characterization
• Experience with rodent models, gene editing, or RNA splicing is strongly preferred
• Some experience with microscopy imaging and immuno-cytochemistry (IHC) techniques
• Histological and immune-histochemical techniques
• First (or co-first) author of one or more peer-reviewed scientific publications
• Excellent English verbal and written communication skills
• Able to work both independently and in a team