Postdoctoral Research Associate in Metabolomics

About the role

The Metabolomics Research Facility is seeking a highly motivated Postdoctoral Research Associate to support collaborative and independent research focused on metabolomics and small molecule analysis using advanced mass spectrometry technologies. This position will play a key role in developing and executing metabolomics workflows for a diverse portfolio of research projects involving biological, environmental, agricultural, pharmaceutical, and biomanufacturing applications.

Responsibilities

• Operate, maintain, and provide training on a variety of analytical instrumentation, including a Thermo Scientific Orbitrap Astral Mass Spectrometer, LC-MS, and GC-MS platforms.
• Collaborate with faculty, staff, students, and external researchers to design experiments, prepare samples, acquire and analyze data, and interpret complex metabolomics datasets.
• Conduct both targeted and non-targeted metabolite profiling of a wide range of sample types, including animal models, human cell lines and cohorts, plants, microbial systems, environmental samples, and other novel biological materials.
• Assist in the development and implementation of new analytical methods and provide scientific consultation to researchers utilizing facility resources.
• Coordinate metabolomics research projects, support the training of laboratory users, contribute to the preparation of scientific reports and publications, and present research findings at professional conferences.
• Participate in ongoing professional development opportunities.

Requirements

• Ph.D. in Biochemistry, Molecular Biology, Analytical Chemistry, Bioinformatics, or a related field.
• Experience working with mass spectrometry instrumentation, associated software platforms, and data analysis workflows.
• Research experience in non-targeted metabolomics, global metabolomics, lipidomics, or closely related fields, including experimental design, sample preparation, data acquisition, data analysis, and post-acquisition bioinformatic and/or statistical analysis.
• Experience analyzing high-resolution LC-MS/MS data generated using Thermo Scientific Orbitrap instrumentation or similar high-resolution mass spectrometry platforms.

Preferred Qualifications

• Experience using Thermo Scientific software applications, including Xcalibur, Compound Discoverer, TraceFinder, and LipidSearch.
• Experience operating, maintaining, troubleshooting, and optimizing complex analytical instrumentation in a research laboratory.
• Experience processing, analyzing, and interpreting raw mass spectrometry data.
• Experience with multi-omics data integration, statistical analysis, and biological interpretation of complex datasets.
• Demonstrated ability to support collaborative research projects and communicate technical findings to diverse scientific audiences.