Postdoctoral Research Associate - Immunology
About the role
Immunology postdoctoral positions are available in Dr. Hongbo Chi's laboratory in the Department of Immunology at St. Jude Children's Research Hospital.
Research focus
The Chi lab investigates immunobiology, immunometabolism and cancer immunology, with a focus on metabolic regulation of the immune system and its therapeutic impacts on cancer and other diseases. Specific areas of interest include:
- Metabolic programs such as amino acid and lipid metabolism
- Signaling pathways including mTOR and nutrient signaling
- Systems-level regulatory networks governing basic T cell and dendritic cell biology and antitumor immunity
Methods and approaches
The lab applies interdisciplinary strategies integrating immunological and genetic approaches with cutting-edge systems immunology and functional genomics tools:
- In vivo CRISPR screening
- Single-cell transcriptomics
- Proteomics
- Metabolomics
- Network reconstruction
Training outcomes
Former trainees of the Chi lab have become principal investigators at multiple academic institutions.
Recent publications
- Cell 187:205 (2024)
- Nature 624:154 (2023)
- Nature 620:200 (2023)
- Nature 623:1034 (2023)
- Nature Reviews Immunology 23:363 (2023)
- Nature 607:135 (2022)
- Nature 600:308 (2021)
- Nature 595:724 (2021)
- Nature 591:306 (2021)
- Cell 184:1245 (2021)
- Nature Reviews Immunology 20:55 (2020)
Benefits and environment
St. Jude Children's Research Hospital, ranked as a best children's hospital for pediatric cancer, offers an exceptional research and training environment with state-of-the-art facilities, competitive salaries, and excellent benefits for postdoctoral fellows. Additional benefits details are available via the hospital's postdoc benefits link.