Postdoctoral Fellow/ Scientist I , Synthetic Spatial Omics

About the role

The newly established Laboratory of Synthetic Spatial Omics at CZ Biohub NY is seeking an exceptional Postdoctoral Fellow/ Scientist I focusing on cell engineering with a creative mindset to drive innovative engineering and investigation of programmable immune cells with single-cell spatial precision.

Responsibilities

• Computationally design programmable molecular components (e.g., receptors and transcription factors).
• Engineer immune cells with these components and profile their behavior in tissue using spatial multi-omics (e.g., seqFISH+) to uncover cellular functions and engineering principles.
• Analyze high-dimensional imaging and sequencing datasets using computational approaches to identify organizational and regulatory principles.
• Collaborate closely with researchers across genomics, immunology, machine learning, and related disciplines.
• Contribute to preprints, publications, presentations, and open science practices.

Requirements

• PhD in Synthetic Biology, Systems Biology, Bioengineering, Immunology or a closely related discipline.
• 2-4 years of experience post PhD (Scientist I) in synthetic biology, immune engineering, and/or protein design.
• Experience developing novel experimental technologies.
• Experience with molecular biology techniques, including cell culture, nucleic acid workflows, and cellular functional assays.
• Ability to independently design rigorous experiments, troubleshoot complex workflows, and drive projects to completion.
• Collaborative mindset and strong scientific communication skills.

Qualifications

• Experience with computational technologies.
• Experience with immune cell engineering and their characterization with animal models.
• Experience with de novo protein design or protein circuits.
• Experience with omics technologies and analysis.

Skills

• Strong computational and analytical skills.
• Excellent problem-solving and critical thinking abilities.
• Effective communication and collaboration skills.

Benefits

We provide a generous employer match on employee 401(k) contributions to support planning for the future. Paid time off to volunteer at an organization of your choice. Funding for select family-forming benefits. Relocation support for employees who need assistance moving.