Postdoctoral Fellow - Sarcoma Medical Oncology - Research

About the role

We are recruiting a highly motivated postdoctoral fellow to join a collaborative research program in sarcoma biology, co-mentored by Dr. Joseph Ludwig and Dr. Danh Truong. This position is designed for scientists with a strong interest in wet-lab experimentation, genome engineering, and in vivo modeling to interrogate the mechanisms that drive aggressive bone and soft-tissue sarcomas.

Responsibilities

• Lead projects focused on CRISPR-based genome engineering, including targeted gene perturbation, pooled screening strategies, and cellular barcoding to study clonal dynamics, tumor evolution, and drug response.
• Conduct experiments across a range of high-fidelity model systems, including engineered cell lines, patient-derived models, and in vivo mouse models of sarcoma.
• Gain extensive experience designing and executing animal studies, tracking clonal behavior over time, and integrating functional perturbations with phenotypic readouts.
• Collaborate effectively across multidisciplinary teams focused on cancer research, including scientists, clinicians, and industry partners.

Requirements

Required qualifications include a PhD (or equivalent) in cancer biology, molecular biology, genetics, bioengineering, or a related discipline. Prior experience with wet-lab molecular biology techniques is essential; experience with CRISPR editing, viral delivery systems, cellular barcoding, or animal models is highly desirable but not required.

Qualifications

We are particularly interested in candidates who are enthusiastic about building and refining experimental models, addressing technically challenging questions, and generating mechanistic insights into rare and understudied cancers. Training will support career development toward academic, industry, or translational research paths.

Skills

The successful candidate will have a strong background in wet-lab molecular biology techniques, including CRISPR editing, viral delivery systems, cellular barcoding, and animal models. They should also possess excellent communication and collaboration skills.

Benefits

The University of Texas MD Anderson Cancer Center offers excellent benefits, including medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and individual and team recognition.

Pay

MD Anderson offers full-time postdoc positions with a salary ranging from $64,000 to $76,000, depending on the number of years of postgraduate experience.

Schedule

This position may be full-time or part-time, depending on the candidate's preference and the needs of the research program.