Jobs · OTHR · Ohio

Postdoctoral Fellow - Olumuyiwa Awoniyi Lab

Cleveland Clinic · Cleveland, OH · 4 wk ago
On-siteOTHR$67k/yrFull-time

About the role

The Awoniyi Laboratory studies how the gut microbiome and its metabolites shape host immunity across the gut–liver axis in primary sclerosing cholangitis (PSC) and PSC-associated colitis. The successful candidate will lead a defined line of investigation within the funded research program, designing and driving experiments that dissect how microbial metabolites reprogram intestinal and liver immune responses.

Responsibilities

- Independent project design with the goal of data generation, analysis, interpretation, and manuscript preparation. - Lead a focused project within the lab’s funded program in host immunology of the gut–liver axis and microbial metabolomic evaluation — from hypothesis and design through analysis and publication. - Apply and extend immunologic approaches — multiparameter flow cytometry and cell sorting, immune-cell isolation and functional assays, tissue immunostaining, and targeted gene-expression profiling — across intestinal and hepatic compartments. - Integrate microbial and metabolomic readouts (short-chain fatty acids, bile acids, and related metabolites) with host immune phenotypes using germ-free and gnotobiotic models and defined bacterial communities. - Analyze and interpret complex datasets, present at lab and national meetings, prepare first-author manuscripts, and contribute to grant applications.

Qualifications

- A PhD or MD/PhD (completed, or expected within ~6 months) in immunology, microbiology, microbiome science, metabolomics, molecular or cell biology, or a closely related discipline. - A strong record of rigorous research, including at least one first-author publication (published or in press). - Hands-on expertise in one or more of: mucosal or hepatic immunology, flow cytometry/cell sorting, mouse models (and IACUC-regulated work), gnotobiotics, microbiome or microbial genomics, or metabolomics/mass spectrometry. - Comfort with quantitative data; interest in computational or bioinformatic analysis is a plus. - Scientific rigor, independence and creativity, strong written and verbal communication, and the collegiality to thrive in a team.

Benefits

- Defined, fundable project within an active grant portfolio. - Deep, hands-on training across a broad platform: gnotobiotics, multiparameter flow cytometry, NanoString and other gene-expression profiling, microbial genomics, and metabolomics. - First-author authorship, national conference presentation, and co-investigator experience on funded work. - A collaborative environment with outstanding core facilities and a deep network of immunology, microbiome, and hepatology investigators.

Pay

- Minimum Annual Salary: $31,200.00 - Maximum Annual Salary: $95,000.00

Other Information

- Nursing Support Career Paths - Benefits Offerings - Adoption assistance - Employee Assistance Program - Employee Hardship Fund # Postdoctoral Fellow – Olumuyiwa Awoniyi Lab ## About the role The Awoniyi Laboratory studies how the gut microbiome and its metabolites shape host immunity across the gut–liver axis in primary sclerosing cholangitis (PSC) and PSC-associated colitis. The successful candidate will lead a defined line of investigation within the funded research program, designing and driving experiments that dissect how microbial metabolites reprogram intestinal and liver immune responses. ## Responsibilities - Independent project design with the goal of data generation, analysis, interpretation, and manuscript preparation. - Lead a focused project within the lab’s funded program in host immunology of the gut–liver axis and microbial metabolomic evaluation — from hypothesis and design through analysis and publication. - Apply and extend immunologic approaches — multiparameter flow cytometry and cell sorting, immune-cell isolation and functional assays, tissue immunostaining, and targeted gene-expression profiling — across intestinal and hepatic compartments. - Integrate microbial and metabolomic readouts (short-chain fatty acids, bile acids, and related metabolites) with host immune phenotypes using germ-free and gnotobiotic models and defined bacterial communities. - Analyze and interpret complex datasets, present at lab and national meetings, prepare first-author manuscripts, and contribute to grant applications. ## Qualifications - A PhD or MD/PhD (completed, or expected within ~6 months) in immunology, microbiology, microbiome science, metabolomics, molecular or cell biology, or a closely related discipline. - A strong record of rigorous research, including at least one first-author publication (published or in press). - Hands-on expertise in one or more of: mucosal or hepatic immunology, flow cytometry/cell sorting, mouse models (and IACUC-regulated work), gnotobiotics, microbiome or microbial genomics, or metabolomics/mass spectrometry. - Comfort with quantitative data; interest in computational or bioinformatic analysis is a plus. - Scientific rigor, independence and creativity, strong written and verbal communication, and the collegiality to thrive in a team. ## Benefits - Defined, fundable project within an active grant portfolio. - Deep, hands-on training across a broad platform: gnotobiotics, multiparameter flow cytometry, NanoString and other gene-expression profiling, microbial genomics, and metabolomics. - First-author authorship, national conference presentation, and co-investigator experience on funded work. - A collaborative environment with outstanding core facilities and a deep network of immunology, microbiome, and hepatology investigators. ## Pay - Minimum Annual Salary: $31,200.00 - Maximum Annual Salary: $95,000.00 ## Other Information - Nursing Support Career Paths - Benefits Offerings - Adoption assistance - Employee Assistance Program - Employee Hardship Fund

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