Postdoctoral Fellow, High-Throughput Functional Genomics

The Team

Biohub is a group of nonprofit research institutes focused on understanding underlying mechanisms of disease and developing new technologies that will lead to actionable diagnostics and effective therapies.

Diversity of thought, ideas, and perspectives

The Biohub values diversity and fosters an inspiring and collaborative environment where all colleagues feel their work contributes to important contributions.

The Opportunity

• Design and execute quantitative, high-throughput experiments linking perturbations to the function of immune and inflammatory systems.
• Develop, optimize, and apply perturbation readout workflows including sequencing-based, imaging-based, or multimodal approaches.
• Collaborate closely with interdisciplinary teams spanning immunology, genomics, computation, and bioengineering.
• Analyze and interpret large-scale, high-dimensional datasets using computational and statistical approaches.
• Disseminate research outputs through high-impact publications, preprints, and open scientific resources.

What You'll Bring

• A PhD in genomics, bioengineering, quantitative biology, systems immunology, computational biology, or a related quantitative life-science field.
• Hands-on experience with core wet-lab molecular and cellular biology techniques, as well as high-throughput profiling methods.
• Demonstrated experience in quantitative molecular and cellular biology techniques and high-throughput profiling approaches.
• Demonstrated expertise in quantitative interpretation of complex, high-dimensional datasets.
• Strong record of scientific productivity, creativity, and collaborative problem-solving in interdisciplinary research environments.
• Motivation to pursue innovative, independent research aligned with the Biohub’s mission and to thrive in a hands-on, team-science culture.
• [Nice to have] Experience with high-throughput profiling platforms (e.g., single-cell RNA-seq, spatial transcriptomics, multiplexed imaging, flow/mass cytometry, or proteomics).
• [Nice to have] Experience working with primary human cells.
• [Nice to have] Experience with technology or assay development, molecular barcoding, novel nucleic acid technologies, or quantitative imaging methods.
• [Nice to have] Background in immunology, inflammation biology, or related disease areas.

Compensation

The Chicago, IL base pay range for a new hire in this role is $71,000-$84,150. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.

Better Together

• This position is an onsite role requiring 100% of the working month, approximately 5 days a week.

Benefits for the Whole You

• Provides a generous employer match on employee 401(k) contributions to support planning for the future.
• Paid time off to volunteer at an organization of your choice.
• Funding for select family-forming benefits.
• Relocation support for employees who need assistance moving.

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