Postdoctoral Associate - Xavier Lab

Description & Requirements

The Broad Institute of MIT & Harvard is seeking a highly motivated Postdoctoral Associate to join the Xavier Lab and Klarman Cell Observatory. The role involves leading data analysis and algorithm development to determine underlying factors contributing to health and disease, with a focus on inflammatory and autoimmune diseases.

Responsibilities

• Oversee data generation and analysis across various internal and external collaborations.
• Perform analyses using current processes and identify, propose, and implement improvements to ensure high-quality datasets.
• Work with other team members and leadership to plan project requirements and timelines, shift priorities as needed, and efficiently execute project tasks.
• Identify and help solve methodological problems, including adjustments to experimental and computational protocols.
• Use single cell and spatial transcriptomic approaches to understand tissue organization and alterations in disease environments such as chronic inflammation.
• Develop novel methods to facilitate exploration of unstructured datasets.
• Write well-crafted, maintainable, scalable, and performant code.
• Lead and carry out projects with minimal supervision.
• Participate in writing papers and grant proposals.
• Present project progress during group meetings.

Qualifications

• Ph.D. in Computational Biology, Computer Science, Physics, Math, Statistics, or related quantitative fields with 0+ years of experience within the field.
• Strong knowledge of a variety of biological areas of research.
• Scientific and numerical programming in Python or R and knowledge of class ML methods and deep learning methods.
• Well versed in a variety of bioinformatic analyses, including Next Generation Sequencing pipelines (single-cell RNA-Seq, single-cell ATAC-Seq, spatial transcriptomics analyses etc...).
• Excellent critical thinking, research, and analytical skills.
• Excellent communication and interpersonal skills and the ability to work with biologists, computational biologists, data scientists, and software engineers.
• Ability to work independently as well as part of a team in a fast-paced, highly collaborative environment.
• Demonstrated ability to carry out a variety of tasks in parallel, recognize and solve problems effectively, and shift priorities rapidly.

Benefits

The Broad Institute offers a competitive benefits package including medical, dental, vision, life, and disability insurance; a 401(k) retirement plan; flexible spending and health savings accounts; at least 13 paid holidays; winter closure; paid time off; parental and family care leave; and an employee assistance program, among other benefits. The institute is an equal opportunity employer.