Post Doctoral Fellow - Knipe Lab

The salary range for this position is $70,000 to $ 71,750 annually.

About the role

The Knipe Lab is looking for a hard-working and enthusiastic post-doctoral candidate to work on a funded project investigating mechanisms of endothelial cell dysfunction in the context of fibrosis in the lungs. This project involves both animal modeling of lung disease (mice) and in vitro cell culture work with human microvascular endothelial cells.

Responsibilities

• Apply scientific expertise and judgement to design, execute, analyze and document in vitro and in vivo studies to define the role of endothelial dysfunction and vascular permeability in the development of fibrosis.
• Hands-on expertise in molecular biology and in vivo disease models.
• Track record of significant contributions to research projects and scientific publications.
• Ability to work independently as well as part of a highly collaborative team.
• Mouse handling, husbandry and disease modeling including dissection and tissue harvesting is required.
• Experience with multiple routes of drug delivery is a plus.
• Aseptic technique and in vitro culture of mammalian cells is required.
• Experience with primary cell isolation is a plus.
• Experience with 3D cultures is also desired but not required.
• Proficiency with molecular biology techniques including western blotting and qRT-PCR is expected.
• Exposure to basics of histology and microscopy including widefield and confocal imaging are a plus.
• Exposure to flow cytometry and cell sorting is a plus.
• Exposure to large data set analysis and/or bioinformatics is a plus.

Qualifications

• Ph.D. in Molecular Biology, Cellular Biology, or a related discipline with 0-1 year of relevant post-graduate experience.

Skills/Abilities/Competencies

• Ability to apply scientific expertise and judgement to design, execute, analyze and document in vitro and in vivo studies to define the role of endothelial dysfunction and vascular permeability in the development of fibrosis.
• Hands-on expertise in molecular biology and in vivo disease models.
• Track record of significant contributions to research projects and scientific publications.
• Ability to work independently as well as part of a highly collaborative team.
• Mouse handling, husbandry and disease modeling including dissection and tissue harvesting is required.
• Experience with multiple routes of drug delivery is a plus.
• Aseptic technique and in vitro culture of mammalian cells is required.
• Experience with primary cell isolation is a plus.
• Experience with 3D cultures is also desired but not required.
• Proficiency with molecular biology techniques including western blotting and qRT-PCR is expected.
• Exposure to basics of histology and microscopy including widefield and confocal imaging are a plus.
• Exposure to flow cytometry and cell sorting is a plus.
• Exposure to large data set analysis and/or bioinformatics is a plus.

Benefits

This position is funded starting in 2026 for three years.

Pay

The salary range for this position is $70,000 to $ 71,750 annually.

Schedule

The position is remote.

Additional Job Details (if Applicable)

Work Location: 75 Francis Street

EEO Statement: 1200 The General Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.

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