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Post-Doctoral Fellow in Lung Biology

University of Pennsylvania Perelman School of Medicine · Erie-Meadville Area · 1 wk ago
AnalystFull-time

About the Role

The Lung Epithelial Biology Laboratory at the Penn Lung Biology Institute (LBI), under the direction of Dr. Michael Beers, has an exceptional opportunity available for Postdoctoral Fellows to join a collaborative research project directed at unraveling the mysteries of idiopathic pulmonary fibrosis and other parenchymal lung diseases. The Beers' Lab has an existing program funded by NIH, the Department of Veterans Affairs, private foundations, and industry to study the molecular mechanisms that regulate tissue injury and repair, focused on discovery, target ID, target validation, and proof of principle studies aimed at uncovering and exploiting novel pathways to treat fibrotic lung diseases.

Research Focus Areas

The postdoctoral fellow can focus the project in any of several related areas using 2 novel published models of lung injury and fibrosis:

  • Epithelial biology
  • Immunological networks
  • Metabolomics
  • Epithelial-mesenchymal crosstalk
  • Transcriptomics/proteomics

See publications: https://www.ncbi.nlm.nih.gov/pubmed/29920187; https://www.ncbi.nlm.nih.gov/pubmed/30910861; https://www.ncbi.nlm.nih.gov/pubmed/30721158

Technologies Available

In addition to unique mouse reagents, the successful candidate will have access to a variety of cutting edge technologies including:

  • RNAseq
  • Single cell and ATAC RNAseq
  • High resolution proteomics
  • CRISPR mediated screens
  • Lineage tracing
  • Organoid assays
  • iPS cells

Requirements

  • PhD in Cell Biology, Biochemistry, Immunology, or related Biomedical Fields
  • Solid background in molecular biology, biochemistry, genetics and cell biology
  • Hands-on experience with animal models, mammalian tissue culture, molecular biology techniques and tissue imaging procedures are required
  • Excellent record of publications in highly respected international scientific journals
  • Familiarity with advanced imaging techniques, transcriptomic profiling, flow cytometry, and/or bioinformatics is desirable

Funding Sources

NIH, Department of Veterans Affairs, and Endowment. Open to US Citizens and Foreign Nationals.

How to Apply

Applications should be uploaded in Interfolio with the link provided. In addition, please email mfbeers@pennmedicine.upenn.edu with subject line "Postdoctoral Fellow Lung Biology" with the following items attached:

  • Current CV
  • Cover letter

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