Pharmacokinetics/PC(PK/PD) Principal Scientist

Key Responsibilities

• Conduct pharmacokinetic (PK), pharmacodynamic (PD), and PK/PD analyses to support clinical development programmes.
• Develop and implement modelling and simulation strategies to inform dose selection, study design, and programme strategy.
• Perform population PK and exposure-response analyses using industry-standard tools.
• Interpret and communicate complex scientific data to multidisciplinary project teams.
• Collaborate with Clinical Pharmacology, Biostatistics, Translational Medicine, Regulatory Affairs, and Clinical Development colleagues.
• Contribute to regulatory submissions, technical reports, publications, and scientific presentations.
• Support the advancement of quantitative clinical pharmacology capabilities across the organisation.

Requirements

• PhD, PharmD, MSc, or equivalent qualification in Pharmacology, Pharmacometrics, Pharmaceutical Sciences, Statistics, Mathematics, Engineering, or a related discipline.
• Experience in PK/PD modelling and simulation within a pharmaceutical, biotechnology, or CRO environment.
• Proficiency with relevant software such as NONMEM, Monolix, Phoenix WinNonlin, R, or equivalent platforms.
• Strong understanding of drug development and clinical pharmacology principles.
• Excellent analytical, communication, and problem-solving skills.
• Able to work effectively within a collaborative, matrixed environment.