PET Chemist

About the role

As a PET Chemist, you will play an essential role in the routine testing, implementation, and validation for radiopharmaceuticals and radiochemicals. The position will have hands-on experience with radiochemistry synthesis, purification, and formulation for in vivo imaging and biodistribution studies; executing studies in parallel; and working alongside other laboratory scientists.

Responsibilities

• Responsible for production of PET radiotracer: Synthesis of generic and novel PET radiopharmaceuticals; purification of small and large molecules; support analytical methods for HPLC, GC and TLC; quality control testing of final product.
• Operate and maintain automated radiochemistry synthesis units.
• Operate and maintain onsite analytical equipment.
• Operate and calibrate laboratory instruments and equipment to produce accurate results.
• Assist with improvement of current cGMP and non-GMP processes.
• Follow all SOP guidelines for manufacturing and QC release testing of radiopharmaceutical product, raw material, finished and semi-finished product, environment, and facilities.
• Maintain a clean and safe work environment, performing radiation safety duties in compliance with safety and pharmaceutical regulations.
• Maintain accurate production and test/validation results.
• Perform other job-related duties as assigned.

Requirements

• Bachelor’s degree in chemistry, Radiology, Nuclear Medicine, Nuclear Physics, Nuclear Engineering, or related field.
• Familiarity with a GMP manufacturing environment and working with FDA and FDA cGMP regulations required.
• Knowledge of molecular imaging techniques and pharmaceutical study design and execution desired.
• Experience with laboratory procedures and radiochemistry techniques (separation techniques – SPE) and analytical method, equipment (ICP-MS, ICP-OES, GC, TLC, and radiometric measures) highly favored.
• Experience with HPLC, radiochemistry synthesis, US FDA cGMP, Radiation Safety Principles, Isotopes production and analytical equipment troubleshooting and maintenance a plus.
• Superior teamwork, multi-tasking and time/project management skills.
• Excellent communication, analytical, problem solving, presentation and computer/PC skills (including proficiency in Microsoft Suite and related software).
• Ability to work varying shifts.

Benefits

• 401(k) retirement benefit program
• Medical and dental care
• Disability insurance
• Employee assistance program
• Extended health care
• Life insurance
• Paid time off
• Vision care