Part-Time Research Assistant, Division of Hematology & Oncology
About the role
Founded in 1819, the University of Cincinnati ranks among the nation’s best urban public research universities, with over 53,600 students, 12,000 faculty and staff, and more than 360,000 living alumni. As a Carnegie 1 institution and anchor of the Cincinnati Innovation District, UC hosts the oldest cooperative education program in the country and an academic health system, and is a member of the Big 12 Conference. The University of Cincinnati College of Medicine, one of the oldest medical schools in the country, trains top‑tier health‑care professionals and conducts cutting‑edge research that improves patient care. The Department of Internal Medicine’s Division of Hematology Oncology is seeking a part‑time Research Assistant to work in Dr. Sarah Skuli’s Lab, which focuses on developing new therapeutic strategies for myeloid malignancies (AML, MDS) with TP53 mutations by studying metabolism and the tumor microenvironment.
Responsibilities
- Follow established research protocols to perform experiments in the lab.
- Design laboratory experiments in coordination with senior laboratory personnel.
- Understand the scientific principles involved in the research and use those principles to troubleshoot and adjust the protocol as appropriate.
- Maintain accurate and detailed records of all laboratory work and experiments.
- Interpret data and assist in judging validity of data; may perform statistical and graphical analysis of data.
- Operate standard laboratory equipment; troubleshoot and correct erroneous results/problems with laboratory equipment and procedures.
- Maintain optimal protocol and assay accuracy by conducting regular quality checks; provide appropriate safety monitoring checks as assigned.
- May assist in training post‑doctoral fellows, graduate students and junior laboratory personnel in laboratory techniques and equipment.
- Maintain inventory and stock of laboratory supplies (including ordering), equipment, and cell cultures.
- Willing and able to assist in daily operations of the laboratory including organization and cleanliness.
- Maintain an active role in laboratory meetings, presentations, publications, which includes contributing material for publications, abstracts and reports.
- Assist with mouse‑based in vivo experiments and may assist with animal colony management and animal husbandry.
Requirements
The role requires continuous sitting, often repetitive hand motion (typing), often hearing/listening, talking, standing, walking, bending, stooping, and often lifting up to 20 pounds. Kneeling or squatting is seldom required. The work environment may involve sufficient noise to necessitate shouting to be heard, hazards such as proximity to moving mechanical parts, moving vehicles, electrical current, working at heights, or exposure to chemicals, and atmospheric conditions including fumes, odors, dusts, mists, gases, or poor ventilation.
Qualifications
- Bachelor’s Degree. Four (4) years of relevant work experience and/or other specialized training can be used in lieu of the education requirement.
- 1+ years of direct basic laboratory experience.
- Experience with routine wet‑lab techniques including mammalian cell culture, molecular biology assays (DNA/RNA/protein extraction/quantification, PCR, qPCR, western blotting, cloning/bacterial transformation), flow cytometry, colorimetric/fluorometric assays, and basic data analysis (Excel/GraphPad). Training will be provided as needed.
- Additional related work experience may be required depending on the field or discipline.